[HTML][HTML] Mesenchymal stem cells: an efficient cell therapy for tendon repair

L Jiang, J Lu, Y Chen, K Lyu… - International …, 2023 - spandidos-publications.com
Tendon injury is a common disorder of the musculoskeletal system caused by overuse or
trauma. With increasing incidence of tendon injuries, it is necessary to find an effective …

Tendon tissue engineering: Current progress towards an optimized tenogenic differentiation protocol for human stem cells

I Donderwinkel, RS Tuan, NR Cameron, JE Frith - Acta Biomaterialia, 2022 - Elsevier
Tendons are integral to our daily lives by allowing movement and locomotion but are
frequently injured, leading to patient discomfort and impaired mobility. Current clinical …

[HTML][HTML] Rescue plan for Achilles: Therapeutics steering the fate and functions of stem cells in tendon wound healing

M Schneider, P Angele, TAH Järvinen… - Advanced drug delivery …, 2018 - Elsevier
Due to the increasing age of our society and a rise in engagement of young people in
extreme and/or competitive sports, both tendinopathies and tendon ruptures present a …

Tendon‐derived extracellular matrix induces mesenchymal stem cell tenogenesis via an integrin/transforming growth factor‐β crosstalk‐mediated mechanism

D Wang, CCM Pun, S Huang, TCM Tang… - The FASEB …, 2020 - Wiley Online Library
Abstract Treatment of tendon injuries is challenging. To develop means to augment tendon
regeneration, we have previously prepared a soluble, low immunogenic (DNA‐free), tendon …

[HTML][HTML] Exosomes from CD133+ human urine-derived stem cells combined adhesive hydrogel facilitate rotator cuff healing by mediating bone marrow mesenchymal …

X Tong, Y Xu, T Zhang, C Deng, J Xun, D Sun… - Journal of Orthopaedic …, 2023 - Elsevier
Background The inadequate regeneration of natural tissue (mainly fibrocartilage) between
tendon and bone during rotator cuff (RC) repair results in an unsatisfactory quality of RC …

Enthesis tissue engineering: biological requirements meet at the interface

I Calejo, R Costa-Almeida, RL Reis… - Tissue Engineering Part …, 2019 - liebertpub.com
Tendon-to-bone interface (enthesis) exhibits a complex multiscale architectural and
compositional organization maintained by a heterogeneous cellular environment …

Tissue-engineered magnetic cell sheet patches for advanced strategies in tendon regeneration

AI Gonçalves, MT Rodrigues, ME Gomes - Acta biomaterialia, 2017 - Elsevier
Tendons are powerful 3D biomechanically structures combining a few cells in an intrincated
and highly hierarchical niche environment. When tendon homeostasis is compromised …

Comparison of tendon development versus tendon healing and regeneration

P He, D Ruan, Z Huang, C Wang, Y Xu… - Frontiers in Cell and …, 2022 - frontiersin.org
Tendon is a vital connective tissue in human skeletal muscle system, and tendon injury is
very common and intractable in clinic. Tendon development and repair are two closely …

Progress with stem cell therapies for tendon tissue regeneration

F Migliorini, M Tingart, N Maffulli - Expert opinion on biological …, 2020 - Taylor & Francis
Introduction Chronic musculoskeletal pain is very prevalent, and accounts for major health-
care expenses. Many of the present therapeutic modalities are only partially effective, and …

Tropoelastin-coated tendon biomimetic scaffolds promote stem cell tenogenic commitment and deposition of elastin-rich matrix

H Almeida, RMA Domingues, SM Mithieux… - … applied materials & …, 2019 - ACS Publications
Tendon tissue engineering strategies that recreate the biophysical and biochemical native
microenvironment have a greater potential to achieve regeneration. Here, we developed …