Advances in catalytic enantioselective fluorination, mono-, di-, and trifluoromethylation, and trifluoromethylthiolation reactions
1. INTRODUCTION Despite being largely absent from natural products and biological
processes, fluorine plays a conspicuous and increasingly important role within …
processes, fluorine plays a conspicuous and increasingly important role within …
Modern approaches for asymmetric construction of carbon–fluorine quaternary stereogenic centers: synthetic challenges and pharmaceutical needs
New methods for preparation of tailor-made fluorine-containing compounds are in extremely
high demand in nearly every sector of chemical industry. The asymmetric construction of …
high demand in nearly every sector of chemical industry. The asymmetric construction of …
Monofluorination of organic compounds: 10 years of innovation
Taking into account the vast arrays of fluorinated motifs known, 11 this review will be limited
to the monofluorination of organic compounds, ie, synthetic methods allowing the …
to the monofluorination of organic compounds, ie, synthetic methods allowing the …
The development of multidimensional analysis tools for asymmetric catalysis and beyond
Conspectus In most modern organic chemistry reports, including many of ours, reaction
optimization schemes are typically presented to showcase how reaction conditions have …
optimization schemes are typically presented to showcase how reaction conditions have …
Late-stage fluorination: fancy novelty or useful tool?
CN Neumann, T Ritter - Angewandte Chemie (International ed. in …, 2015 - europepmc.org
Charming fluorine: This Essay examines the recent surge in late-stage fluorination reactions
and outlines challenges that need to be overcome to increase the impact of modern …
and outlines challenges that need to be overcome to increase the impact of modern …
The Deuterated “Magic Methyl” Group: A Guide to Site‐Selective Trideuteromethyl Incorporation and Labeling by Using CD3 Reagents
In the field of medicinal chemistry, the precise installation of a trideuteromethyl group is
gaining ever‐increasing attention. Site‐selective incorporation of the deuterated “magic …
gaining ever‐increasing attention. Site‐selective incorporation of the deuterated “magic …
Addition and correction to complete field guide to asymmetric BINOL-phosphate derived Brønsted acid and metal catalysis: History and classification by mode of …
D Parmar, E Sugiono, S Raja, M Rue** - Chemical Reviews, 2017 - ACS Publications
Figure 73: The proposed catalyst/substrate interaction shown in Figure 73 corresponds to
the related sulfoxidation catalyzed by chiral phosphoric acid PA 5 (ref 133). Please note that …
the related sulfoxidation catalyzed by chiral phosphoric acid PA 5 (ref 133). Please note that …
Chiral Selenide-Catalyzed Enantioselective Allylic Reaction and Intermolecular Difunctionalization of Alkenes: Efficient Construction of C-SCF3 Stereogenic …
X Liu, Y Liang, J Ji, J Luo, X Zhao - Journal of the American …, 2018 - ACS Publications
New approaches for the synthesis of enantiopure trifluoromethylthiolated molecules by
chiral selenide-catalyzed allylic trifluoromethylthiolation and intermolecular …
chiral selenide-catalyzed allylic trifluoromethylthiolation and intermolecular …
Stereoselectivity and substrate specificity of the Fe (II)/α-ketoglutarate-dependent oxygenase TqaL
Non-heme iron enzymes are versatile catalysts in the biosynthesis of medicinal natural
products and have attracted increasing attention as practical catalytic tools in chemical …
products and have attracted increasing attention as practical catalytic tools in chemical …
Catalytic dynamic kinetic resolutions in tandem to construct two-axis terphenyl atropisomers
OM Beleh, E Miller, FD Toste… - Journal of the American …, 2020 - ACS Publications
The defined structure of molecules bearing multiple stereogenic axes is of increasing
relevance to materials science, pharmaceuticals, and catalysis. However, catalytic …
relevance to materials science, pharmaceuticals, and catalysis. However, catalytic …