Presynaptic calcium channels: specialized control of synaptic neurotransmitter release

AC Dolphin, A Lee - Nature Reviews Neuroscience, 2020 - nature.com
Chemical synapses are heterogeneous junctions formed between neurons that are
specialized for the conversion of electrical impulses into the exocytotic release of …

[HTML][HTML] Genetic disruption of voltage-gated calcium channels in psychiatric and neurological disorders

S Heyes, WS Pratt, E Rees, S Dahimene, L Ferron… - Progress in …, 2015 - Elsevier
This review summarises genetic studies in which calcium channel genes have been
connected to the spectrum of neuropsychiatric syndromes, from bipolar disorder and …

Genetic associations between voltage-gated calcium channels and psychiatric disorders

A Andrade, A Brennecke, S Mallat, J Brown… - International journal of …, 2019 - mdpi.com
Psychiatric disorders are mental, behavioral or emotional disorders. These conditions are
prevalent, one in four adults suffer from any type of psychiatric disorders world-wide. It has …

Voltage-gated calcium channels: key players in sensory coding in the retina and the inner ear

T Pangrsic, JH Singer, A Koschak - Physiological reviews, 2018 - journals.physiology.org
Calcium influx through voltage-gated Ca (CaV) channels is the first step in synaptic
transmission. This review concerns CaV channels at ribbon synapses in primary sense …

Voltage-and calcium-gated ion channels of neurons in the vertebrate retina

MJ Van Hook, S Nawy, WB Thoreson - Progress in retinal and eye research, 2019 - Elsevier
In this review, we summarize studies investigating the types and distribution of voltage-and
calcium-gated ion channels in the different classes of retinal neurons: rods, cones …

Functions of presynaptic voltage-gated calcium channels

AC Dolphin - Function, 2021 - academic.oup.com
Voltage-gated calcium channels are the principal conduits for depolarization-mediated
Ca2+ entry into excitable cells. In this review, the biophysical properties of the relevant …

Transmission at rod and cone ribbon synapses in the retina

WB Thoreson - Pflügers Archiv-European Journal of Physiology, 2021 - Springer
Light-evoked voltage responses of rod and cone photoreceptor cells in the vertebrate retina
must be converted to a train of synaptic vesicle release events for transmission to …

The auxiliary calcium channel subunit α2δ4 is required for axonal elaboration, synaptic transmission, and wiring of rod photoreceptors

Y Wang, KE Fehlhaber, I Sarria, Y Cao, NT Ingram… - Neuron, 2017 - cell.com
Neural circuit wiring relies on selective synapse formation whereby a presynaptic release
apparatus is matched with its cognate postsynaptic machinery. At metabotropic synapses …

The role of auxiliary subunits for the functional diversity of voltage‐gated calcium channels

M Campiglio, BE Flucher - Journal of cellular physiology, 2015 - Wiley Online Library
Voltage‐gated calcium channels (VGCCs) represent the sole mechanism to convert
membrane depolarization into cellular functions like secretion, contraction, or gene …

Circadian regulation in the retina: from molecules to network

GYP Ko - European Journal of Neuroscience, 2020 - Wiley Online Library
The mammalian retina is the most unique tissue among those that display robust
circadian/diurnal oscillations. The retina is not only a light sensing tissue that relays light …