Reactive oxygen species (ROS) are bioproducts of cellular metabolism. There is a range of
molecules with oxidizing properties known as ROS. Despite those molecules being implied …

Chronic kidney disease (CKD) is a major public health concern, underscoring a need to
identify pathogenic mechanisms and potential therapeutic targets. Reactive oxygen species …

Nitric oxide (NO) is one of the most important molecules released by endothelial cells, and
its antiatherogenic properties support cardiovascular homeostasis. Diminished NO …

Cardiovascular pathologies maintain the leading position in mortality worldwide.
Atherosclerosis is a chronic disease that can result in a variety of serious complications …

Nitric oxide (NO) is a small free radical with critical signaling roles in physiology and
pathophysiology. The generation of sufficient NO levels to regulate the resistance of the …

Endothelial cells (ECs) are more than inert blood vessel lining material. Instead, they are
active players in the formation of new blood vessels (angiogenesis) both in health and (life …

The B-vitamins comprise a group of eight water soluble vitamins that perform essential,
closely inter-related roles in cellular functioning, acting as co-enzymes in a vast array of …

The Global Burden of Disease Study identified cardiovascular risk factors as leading causes
of global deaths and life years lost. Endothelial dysfunction represents a pathomechanism …

Higher organisms rely on a closed cardiovascular circulatory system with blood vessels
supplying vital nutrients and oxygen to distant tissues. Not surprisingly, vascular pathologies …

Abstract The European Cooperation in Science and Technology (COST) provides an ideal
framework to establish multi-disciplinary research networks. COST Action BM1203 (EU …