Bacteriophage therapy against Pseudomonas aeruginosa biofilms: a review

Z Chegini, A Khoshbayan, M Taati Moghadam… - Annals of clinical …, 2020 - Springer
Abstract Multi-Drug Resistant (MDR) Pseudomonas aeruginosa is one of the most important
bacterial pathogens that causes infection with a high mortality rate due to resistance to …

Bacterial biofilm destruction: A focused review on the recent use of phage-based strategies with other antibiofilm agents

S Amankwah, K Abdella, T Kassa - Nanotechnology, science and …, 2021 - Taylor & Francis
Biofilms are bacterial communities that live in association with biotic or abiotic surfaces and
enclosed in an extracellular polymeric substance. Their formation on both biotic and abiotic …

Phages against pathogenic bacterial biofilms and biofilm-based infections: a review

S Liu, H Lu, S Zhang, Y Shi, Q Chen - Pharmaceutics, 2022 - mdpi.com
Bacterial biofilms formed by pathogens are known to be hundreds of times more resistant to
antimicrobial agents than planktonic cells, making it extremely difficult to cure biofilm-based …

[HTML][HTML] A perfect fit: Bacteriophage receptor-binding proteins for diagnostic and therapeutic applications

J Klumpp, M Dunne, MJ Loessner - Current opinion in microbiology, 2023 - Elsevier
Bacteriophages are the most abundant biological entity on earth, acting as the predators
and evolutionary drivers of bacteria. Owing to their inherent ability to specifically infect and …

Bacteriophage-mediated control of biofilm: a promising new dawn for the future

C Chang, X Yu, W Guo, C Guo, X Guo, Q Li… - Frontiers in …, 2022 - frontiersin.org
Biofilms are complex microbial microcolonies consisting of planktonic and dormant bacteria
bound to a surface. The bacterial cells within the biofilm are embedded within the …

The mechanism of bacterial resistance and potential bacteriostatic strategies

F Zhang, W Cheng - Antibiotics, 2022 - mdpi.com
Bacterial drug resistance is rapidly develo** as one of the greatest threats to human
health. Bacteria will adopt corresponding strategies to crack the inhibitory effect of antibiotics …

Understanding the complex phage-host interactions in biofilm communities

DP Pires, LDR Melo, J Azeredo - Annual Review of Virology, 2021 - annualreviews.org
Bacteriophages and bacterial biofilms are widely present in natural environments, a fact that
has accelerated the evolution of phages and their bacterial hosts in these particular niches …

Biological foundations of successful bacteriophage therapy

C Venturini, A Petrovic Fabijan… - EMBO Molecular …, 2022 - embopress.org
Bacteriophages (phages) are selective viral predators of bacteria. Abundant and ubiquitous
in nature, phages can be used to treat bacterial infections (phage therapy), including …

Enzymatic dispersion of biofilms: An emerging biocatalytic avenue to combat biofilm-mediated microbial infections

R Ramakrishnan, AK Singh, S Singh… - Journal of Biological …, 2022 - ASBMB
Drug resistance by pathogenic microbes has emerged as a matter of great concern to
mankind. Microorganisms such as bacteria and fungi employ multiple defense mechanisms …

Targeting biofilms using phages and their enzymes

J Azeredo, P Garcia, Z Drulis-Kawa - Current Opinion in Biotechnology, 2021 - Elsevier
Highlights•Biofilms are highly tolerant to antimicrobials due to its sophisticated microbial
organization and matrix composition.•The extracellular matrix components are potential …