The cellular lives of Wolbachia
Wolbachia are successful Gram-negative bacterial endosymbionts, globally infecting a large
fraction of arthropod species and filarial nematodes. Efficient vertical transmission, the …
fraction of arthropod species and filarial nematodes. Efficient vertical transmission, the …
Endoreplication: polyploidy with purpose
A great many cell types are necessary for the myriad capabilities of complex, multicellular
organisms. One interesting aspect of this diversity of cell type is that many cells in diploid …
organisms. One interesting aspect of this diversity of cell type is that many cells in diploid …
Genetics on the Fly: A Primer on the Drosophila Model System
Fruit flies of the genus Drosophila have been an attractive and effective genetic model
organism since Thomas Hunt Morgan and colleagues made seminal discoveries with them …
organism since Thomas Hunt Morgan and colleagues made seminal discoveries with them …
Signatures of Majorana fermions in hybrid superconductor-semiconductor nanowire devices
Majorana fermions are particles identical to their own antiparticles. They have been
theoretically predicted to exist in topological superconductors. Here, we report electrical …
theoretically predicted to exist in topological superconductors. Here, we report electrical …
Cell polarity in eggs and epithelia: parallels and diversity
Cell polarity, the generation of cellular asymmetries, is necessary for diverse processes in
animal cells, such as cell migration, asymmetric cell division, epithelial barrier function, and …
animal cells, such as cell migration, asymmetric cell division, epithelial barrier function, and …
The WAVE regulatory complex links diverse receptors to the actin cytoskeleton
The WAVE regulatory complex (WRC) controls actin cytoskeletal dynamics throughout the
cell by stimulating the actin-nucleating activity of the Arp2/3 complex at distinct membrane …
cell by stimulating the actin-nucleating activity of the Arp2/3 complex at distinct membrane …
aPKC phosphorylation of Bazooka defines the apical/lateral border in Drosophila epithelial cells
Summary Bazooka (PAR-3), PAR-6, and aPKC form a complex that plays a key role in the
polarization of many cell types. In epithelial cells, however, Bazooka localizes below PAR-6 …
polarization of many cell types. In epithelial cells, however, Bazooka localizes below PAR-6 …
mTAIL-seq reveals dynamic poly (A) tail regulation in oocyte-to-embryo development
Eukaryotic mRNAs are subject to multiple types of tailing that critically influence mRNA
stability and translatability. To investigate RNA tails at the genomic scale, we previously …
stability and translatability. To investigate RNA tails at the genomic scale, we previously …
A single-cell atlas and lineage analysis of the adult Drosophila ovary
The Drosophila ovary is a widely used model for germ cell and somatic tissue biology. Here
we use single-cell RNA-sequencing (scRNA-seq) to build a comprehensive cell atlas of the …
we use single-cell RNA-sequencing (scRNA-seq) to build a comprehensive cell atlas of the …
The Hippo pathway integrates PI3K–Akt signals with mechanical and polarity cues to control tissue growth
N Borreguero-Muñoz, GC Fletcher… - PLoS …, 2019 - journals.plos.org
The Hippo signalling pathway restricts cell proliferation in animal tissues by inhibiting Yes-
associated protein (YAP or YAP1) and Transcriptional Activator with a PDZ domain (TAZ or …
associated protein (YAP or YAP1) and Transcriptional Activator with a PDZ domain (TAZ or …