Molecular rotors: fluorescent sensors for microviscosity and conformation of biomolecules
The viscosity and crowding of biological environment are considered vital for the correct
cellular function, and alterations in these parameters are known to underly a number of …
cellular function, and alterations in these parameters are known to underly a number of …
Fatty acids in cancer chemoresistance
J Qin, L Ye, X Wen, X Zhang, Y Di, Z Chen, Z Wang - Cancer Letters, 2023 - Elsevier
Despite the remarkable clinical success of immunotherapy and molecular targeted therapy
in patients with advanced tumors, chemotherapy remains the most commonly used …
in patients with advanced tumors, chemotherapy remains the most commonly used …
Selective visualization of tumor cell membranes and tumors with a viscosity-sensitive plasma membrane probe
Q Li, W Zhu, S Gong, S Jiang, G Feng - Analytical Chemistry, 2023 - ACS Publications
Cancer is a worldwide health problem. Revealing the changes in the microenvironment after
cell carcinogenesis is helpful to understand cancer and develop sensitive methods for …
cell carcinogenesis is helpful to understand cancer and develop sensitive methods for …
Polarity-sensitive and membrane-specific probe quantitatively monitoring ferroptosis through fluorescence lifetime imaging
S Wu, Y Yan, H Hou, Z Huang, D Li, X Zhang… - Analytical …, 2022 - ACS Publications
As a new form of regulated cell death, ferroptosis is closely related to various diseases. To
interpret this biological behavior and monitor related pathological processes, it is necessary …
interpret this biological behavior and monitor related pathological processes, it is necessary …
Sensing cholesterol-induced rigidity in model membranes with time-resolved fluorescence spectroscopy and microscopy
Here, we report the characterization of cholesterol levels on membrane fluidity with a twisted
intramolecular charge transfer (TICT) membrane dye, namely DI-8-ANEPPS, using …
intramolecular charge transfer (TICT) membrane dye, namely DI-8-ANEPPS, using …
Correlation of Plasma Membrane Microviscosity and Cell Stiffness Revealed via Fluorescence-Lifetime Imaging and Atomic Force Microscopy
The biophysical properties of cells described at the level of whole cells or their membranes
have many consequences for their biological behavior. However, our understanding of the …
have many consequences for their biological behavior. However, our understanding of the …
Understanding the Mechanism of Light-Induced Age-Related Decrease in Melanin Concentration in Retinal Pigment Epithelium Cells
AE Dontsov, MA Yakovleva, AA Vasin, AA Gulin… - International Journal of …, 2023 - mdpi.com
It is known that during the process of aging, there is a significant decrease in the number of
melanosomes in the retinal pigment epithelium (RPE) cells in the human eye. Melanosomes …
melanosomes in the retinal pigment epithelium (RPE) cells in the human eye. Melanosomes …
[HTML][HTML] Cholesterol metabolism in pancreatic cancer and associated therapeutic strategies
T Daya, A Breytenbach, L Gu, M Kaur - … BBA)-Molecular and Cell Biology of …, 2024 - Elsevier
Pancreatic cancer remains one of the most lethal cancers due to late diagnosis and high
chemoresistance. Despite recent progression in the development of chemotherapies …
chemoresistance. Despite recent progression in the development of chemotherapies …
Dysregulation of cellular membrane homeostasis as a crucial modulator of cancer risk
Cellular membranes serve as an epicentre combining extracellular and cytosolic
components with membranous effectors, which together support numerous fundamental …
components with membranous effectors, which together support numerous fundamental …
[HTML][HTML] The Utility of Lipidomic Analysis in Colorectal Cancer Diagnosis and Prognosis—A Systematic Review of Recent Literature
J Klekowski, M Chabowski… - International Journal of …, 2024 - mdpi.com
Colorectal cancer (CRC) is among the most prevalent and lethal malignancies. Lipidomic
investigations have revealed numerous disruptions in lipid profiles across various cancers …
investigations have revealed numerous disruptions in lipid profiles across various cancers …