The evolution of macrophages has made them primordial for both development and
immunity. Their functions range from the sha** of body plans to the ingestion and …

The phylum Actinobacteria harbors many important human pathogens and also provides
one of the richest sources of natural products, including numerous antibiotics and other …

In this paper, we present the MycoBrowser portal (http://mycobrowser. epfl. ch/), a resource
that provides both in silico generated and manually reviewed information within databases …

Because genetically monomorphic bacterial pathogens harbour little DNA sequence
diversity, most current genoty** techniques used to study the epidemiology of these …

Buruli ulcer is a neglected emerging disease that has recently been reported in some
countries as the second most frequent mycobacterial disease in humans after tuberculosis …

The dysregulated phosphatidylinositol-3-kinase (PI3K)-Akt-mammalian target of rapamycin
(mTOR) signaling pathway has been implicated in various immune-mediated inflammatory …

Mycobacterium lepromatosis is an uncultured human pathogen associated with diffuse
lepromatous leprosy and a reactional state known as Lucio's phenomenon. By using deep …

Many species within the genus Mycobacterium are prominent pathogens, above all
members of the M. tuberculosis complex, M. leprae, and M. ulcerans. In addition, there are …

Background Genome size and gene content in bacteria are associated with their lifestyles.
Obligate intracellular bacteria (ie, mutualists and parasites) have small genomes that …

Infection with Mycobacterium ulcerans is characterised by tissue necrosis and
immunosuppression due to mycolactone, the necessary and sufficient virulence factor for …