The renin–angiotensin system (RAS) has recently been extended by the addition of a novel
axis consisting of the angiotensin-converting enzyme 2 (ACE2), the heptapeptide …

The Ang II (Angiotensin II)-Angiotensin-(1-7) axis of the Renin Angiotensin System
encompasses 3 enzymes that form Angiotensin-(1-7)[Ang-(1-7)] directly from Ang II: ACE2 …

The intrarenal renin–angiotensin system (RAS) has many well-documented
pathophysiologic functions in both blood pressure regulation and renal disease …

Multigene families encoding diverse secreted peptide hormones play important roles in
plant development. A need exists to efficiently elucidate the structures and post-translational …

All proteins end with a carboxyl terminus that has unique biophysical properties and is often
disordered. Although there are examples of important C-termini functions, a more global role …

Recent studies have provided further evidence for the presence of many components of the
RAS in glomerular structures, which supports the importance of locally produced …

Among the various comorbidities potentially worsening the clinical outcome in patients
hospitalized for the acute respiratory syndrome coronavirus-2 (SARS-CoV-2), hypertension …

The role of a dysregulated renin-angiotensin system (RAS) in the pathogenesis of COVID-19
is well recognized. The imbalance between angiotensin II (Ang II) and Angiotensin 1-7 (Ang …

Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are accompanied by
high mortality rates and few effective treatments. Transplantation of human placental …

The article describes the possible pathophysiological origin of COVID-19 and the crucial
role of renin-angiotensin system (RAS), providing several “converging” evidence in support …