Necrotizing enterocolitis (NEC) is the most frequent and lethal disease of the gastrointestinal
tract of preterm infants. At present, NEC is thought to develop in the premature host in the …

Since their discovery nearly 25 years ago, the BCL-2 family members BNIP3 and BNIP3L
(aka Nix) have been labelled 'atypical'. Originally, this was because BNIP3 and Nix have …

The function of the intestinal barrier is partially dependent on host maturity and the
colonization patterns of the microbiome to which it is exposed. Premature birth and stressors …

Necrotizing enterocolitis (NEC) is the most devastating gastrointestinal disease of
prematurity. Although the precise cause is not well understood, the main risk factors thought …

Necrotizing enterocolitis (NEC) is an idiopathic, inflammatory bowel necrosis of premature
infants. Clinical studies have linked NEC with antecedent red blood cell (RBC) transfusions …

Better means to diagnose and define necrotizing enterocolitis are needed to guide clinical
practice and research. Adequacy of Bell's staging system for clinical practice and clarity of …

Background: Necrotizing enterocolitis (NEC) is an inflammatory bowel necrosis of premature
infants. Based on our recent findings of increased Smad7 expression in surgically resected …

Objective Determine whether hematological and transfusion patterns following, the onset of
NEC can identify infants likely to develop fulminant, fatal necrotizing enterocolitis (NEC) …

Necrotizing enterocolitis (NEC) is a devastating disease of prematurity, with no current
method with sufficient sensitivity and specificity for early diagnosis. It affects approximately …

In recent years, several studies have shown that premature infants who develop NEC
frequently display enteric dysbiosis with increased Gram-negative bacteria for several days …