Evolution of drug resistance in Mycobacterium tuberculosis: a review on the molecular determinants of resistance and implications for personalized care
N Dookie, S Rambaran, N Padayatchi… - Journal of …, 2018 - academic.oup.com
Abstract Drug-resistant TB (DR-TB) remains a significant challenge in TB treatment and
control programmes worldwide. Advances in sequencing technology have significantly …
control programmes worldwide. Advances in sequencing technology have significantly …
Drug Resistance Mechanisms in Mycobacterium tuberculosis
JC Palomino, A Martin - Antibiotics, 2014 - mdpi.com
Tuberculosis (TB) is a serious public health problem worldwide. Its situation is worsened by
the presence of multidrug resistant (MDR) strains of Mycobacterium tuberculosis, the …
the presence of multidrug resistant (MDR) strains of Mycobacterium tuberculosis, the …
Molecular basis and mechanisms of drug resistance in Mycobacterium tuberculosis: classical and new drugs
PE Almeida Da Silva… - Journal of antimicrobial …, 2011 - academic.oup.com
Tuberculosis (TB) remains one of the leading public health problems worldwide. Declared
as a global emergency in 1993 by the WHO, its control is hampered by the emergence of …
as a global emergency in 1993 by the WHO, its control is hampered by the emergence of …
[HTML][HTML] Exploring the potential of endophytes from medicinal plants as sources of antimycobacterial compounds
A Alvin, KI Miller, BA Neilan - Microbiological research, 2014 - Elsevier
Natural product drug discovery has regained interest due to low production costs, structural
diversity, and multiple uses of active compounds to treat various diseases. Attention has …
diversity, and multiple uses of active compounds to treat various diseases. Attention has …
PoPMuSiC 2.1: a web server for the estimation of protein stability changes upon mutation and sequence optimality
Background The rational design of modified proteins with controlled stability is of extreme
importance in a whole range of applications, notably in the biotechnological and …
importance in a whole range of applications, notably in the biotechnological and …
Antibiotic resistance mechanisms in M. tuberculosis: an update
L Nguyen - Archives of toxicology, 2016 - Springer
Abstract Treatment of tuberculosis (TB) has been a therapeutic challenge because of not
only the naturally high resistance level of Mycobacterium tuberculosis to antibiotics but also …
only the naturally high resistance level of Mycobacterium tuberculosis to antibiotics but also …
Mechanisms of drug resistance in Mycobacterium tuberculosis: update 2015
Y Zhang, WW Yew - … Journal of Tuberculosis and Lung Disease, 2015 - ingentaconnect.com
Drug-resistant tuberculosis (DR-TB), including multi-and extensively drug-resistant TB, is
posing a significant challenge to effective treatment and TB control worldwide. New progress …
posing a significant challenge to effective treatment and TB control worldwide. New progress …
Molecular Targets Related Drug Resistance Mechanisms in MDR-, XDR-, and TDR-Mycobacterium tuberculosis Strains
Tuberculosis (TB) is a formidable infectious disease that remains a major cause of death
worldwide today. Escalating application of genomic techniques has expedited the …
worldwide today. Escalating application of genomic techniques has expedited the …
Deciphering drug resistance in Mycobacterium tuberculosis using whole-genome sequencing: progress, promise, and challenges
Tuberculosis (TB) is a global infectious threat that is intensified by an increasing incidence of
highly drug-resistant disease. Whole-genome sequencing (WGS) studies of Mycobacterium …
highly drug-resistant disease. Whole-genome sequencing (WGS) studies of Mycobacterium …
New insights in to the intrinsic and acquired drug resistance mechanisms in mycobacteria
Infectious diseases caused by clinically important Mycobacteria continue to be an important
public health problem worldwide primarily due to emergence of drug resistance crisis. In …
public health problem worldwide primarily due to emergence of drug resistance crisis. In …