Blood-brain delivery methods using nanotechnology

DM Teleanu, C Chircov, AM Grumezescu, A Volceanov… - Pharmaceutics, 2018 - mdpi.com
Pathologies of the brain, of which brain cancer, Alzheimer's disease, Parkinson's disease,
stroke, and multiple sclerosis, are some of the most prevalent, and that presently are poorly …

All‐in‐One nanomedicine: multifunctional single‐component nanoparticles for cancer theranostics

Y Cai, X Chen, J Si, X Mou, X Dong - Small, 2021 - Wiley Online Library
The development of cancer diagnostic imaging and treatment is a major concern worldwide.
By integrating imaging and therapy into one theranostic nanoplatform for simultaneously …

Overcoming the blood–brain barrier. challenges and tricks for CNS drug delivery

LA Bors, F Erdő - Scientia Pharmaceutica, 2019 - mdpi.com
Treatment of certain central nervous system disorders, including different types of cerebral
malignancies, is limited by traditional oral or systemic administrations of therapeutic drugs …

An overview of nanotechnologies for drug delivery to the brain

A Ayub, S Wettig - Pharmaceutics, 2022 - mdpi.com
Drug delivery to the brain has been one of the toughest challenges researchers have faced
to develop effective treatments for brain diseases. Owing to the blood–brain barrier (BBB) …

Brain-targeted delivery shuttled by black phosphorus nanostructure to treat Parkinson's disease

S **ong, Z Li, Y Liu, Q Wang, J Luo, X Chen, Z **e… - Biomaterials, 2020 - Elsevier
The treatment of Parkinson's disease (PD) is hampered by the blood-brain barrier (BBB). As
such, there is an urgent need for the development of a novel nanoplatform capable of …

Blood–brain barrier transporters: opportunities for therapeutic development in ischemic stroke

KL Nilles, EI Williams, RD Betterton, TP Davis… - International Journal of …, 2022 - mdpi.com
Globally, stroke is a leading cause of death and long-term disability. Over the past decades,
several efforts have attempted to discover new drugs or repurpose existing therapeutics to …

Advanced drug delivery system against ischemic stroke

S Zhang, Y Zhou, R Li, Z Chen, X Fan - Journal of Controlled Release, 2022 - Elsevier
Ischemic stroke is a vascular central nervous system (CNS) disease that leads a disability
and death. Thrombolysis and neuroprotection are the primary treatment strategies of …

Polymeric dendrimers as nanocarrier vectors for neurotheranostics

H Li, S Zha, H Li, H Liu, KL Wong, AH All - Small, 2022 - Wiley Online Library
Dendrimers are polymers with well‐defined 3D branched structures that are vastly utilized in
various neurotheranostics and biomedical applications, particularly as nanocarrier vectors …

Advances of nano drug delivery system for the theranostics of ischemic stroke

W Lv, Y Liu, S Li, L Lv, H Lu, H **n - Journal of nanobiotechnology, 2022 - Springer
From the global perspective, stroke refers to a highly common cause of disability and death.
Ischemic stroke (IS), attributed to blood vessel blockage, preventing the flow of blood to …

Polymeric nanocarriers delivery systems in ischemic stroke for targeted therapeutic strategies

L Zhu, W Zhong, X Meng, X Yang, W Zhang… - Journal of …, 2024 - Springer
Ischemic stroke is a complex, high-mortality disease with multifactorial etiology and
pathogenesis. Currently, drug therapy is mainly used treat ischemic stroke in clinic, but there …