Animal behavior is shaped by a variety of" internal states"—partially hidden variables that
profoundly shape perception, cognition, and action. The neural basis of internal states, such …

Neural activity and behavior are both notoriously variable, with responses differing widely
between repeated presentation of identical stimuli or trials. Recent results in humans and …

Rapid variations in cortical state during wakefulness have a strong influence on neural and
behavioural responses and are tightly coupled to changes in pupil size across species …

The mechanistic link between neural circuit activity and behavior remains unclear. While
manipulating cortical activity can bias certain behaviors and elicit artificial percepts, some …

Recent work continues to place cholinergic circuits at center stage for normal executive and
mnemonic functioning and provides compelling evidence that the loss of cholinergic …

The neurovisceral integration (NVI) model was originally proposed to account for observed
relationships between peripheral physiology, cognitive performance, and emotional/physical …

The state of the brain and body constantly varies on rapid and slow timescales. These
variations contribute to the apparent noisiness of sensory responses at both the neural and …

The mammalian basal forebrain (BF) has important roles in controlling sleep and
wakefulness, but the underlying neural circuit remains poorly understood. We examined the …

Neural responses are modulated by brain state, which varies with arousal, attention, and
behavior. In mice, running and whisking desynchronize the cortex and enhance sensory …

In the long-term, with progression of the illness, Parkinson's disease dementia affects up to
90% of patients with Parkinson's disease. With increasing life expectancy in western …