Objectives To determine the diagnostic accuracy of ultrasound at 11–14 weeks' gestation in
the detection of fetal cardiac abnormalities and to evaluate factors that impact the detection …

Fetal structural anomalies are found in up to 3% of all pregnancies and ultrasound-based
screening has been an integral part of routine prenatal care for decades. The prenatal …

Performing a routine first-trimester ultrasound examination at 11+ 0 to 14+ 0 weeks'
gestation is of value for confirming viability and plurality, accurate pregnancy dating …

Background First-trimester ultrasound scans were introduced to China for nearly 20 years.
The ability of first-trimester ultrasound screening to detect different malformations was …

Screening for chromosomal disorders, especially for trisomy 21, has undergone a number of
changes in the last 50 years. Today, cell-free DNA analysis (cfDNA) is the gold standard in …

Objective The purpose of this study was to explore the diagnostic yield and clinical utility of
trio‐based rapid whole exome sequencing (rWES) in pregnancies of fetuses with a wide …

Objectives The main aim of this study was to assess the proportion and type of congenital
anomalies, both structural and chromosomal, that can be detected at an early scan …

Most brain abnormalities are present in the first trimester, but only a few are detected so
early in gestation. According to current recommendations for first‐trimester ultrasound, the …

Objectives To give an overview of the genetic and structural abnormalities occurring in
fetuses with nuchal translucency (NT) measurement exceeding the 95th percentile at first …

The most frequently asked questions that confront the fetal medicine trainee/expert on a
daily basis are “Is the finding real or merely an artifact?” and “Is the diagnosis correct?” …