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Recent progress in the science of complex coacervation
Complex coacervation is an associative, liquid–liquid phase separation that can occur in
solutions of oppositely-charged macromolecular species, such as proteins, polymers, and …
solutions of oppositely-charged macromolecular species, such as proteins, polymers, and …
Complex coacervate‐based materials for biomedicine
There has been increasing interest in complex coacervates for deriving and transporting
biomaterials. Complex coacervates are a dense, polyelectrolyte‐rich liquid that results from …
biomaterials. Complex coacervates are a dense, polyelectrolyte‐rich liquid that results from …
Development of the modern theory of polymeric complex coacervation
CE Sing - Advances in colloid and interface science, 2017 - Elsevier
Oppositely charged polymers can undergo the process of complex coacervation, which
refers to a liquid–liquid phase separation driven by electrostatic attraction. These materials …
refers to a liquid–liquid phase separation driven by electrostatic attraction. These materials …
Protein encapsulation via polypeptide complex coacervation
Proteins have gained increasing success as therapeutic agents; however, challenges exist
in effective and efficient delivery. In this work, we present a simple and versatile method for …
in effective and efficient delivery. In this work, we present a simple and versatile method for …
Formation of multiphase complex coacervates and partitioning of biomolecules within them
GA Mountain, CD Keating - Biomacromolecules, 2019 - ACS Publications
Biological systems employ liquid–liquid phase separation to localize macromolecules and
processes. The properties of intracellular condensates that allow for multiple, distinct liquid …
processes. The properties of intracellular condensates that allow for multiple, distinct liquid …
Chirality-selected phase behaviour in ionic polypeptide complexes
Polyelectrolyte complexes present new opportunities for self-assembled soft matter. Factors
determining whether the phase of the complex is solid or liquid remain unclear. Ionic …
determining whether the phase of the complex is solid or liquid remain unclear. Ionic …
The effect of salt on the complex coacervation of vinyl polyelectrolytes
Complex coacervation is an electrostatically-driven phase separation phenomenon that is
utilized in a wide range of everyday applications and is of great interest for the creation of …
utilized in a wide range of everyday applications and is of great interest for the creation of …
Protein encapsulation using complex coacervates: what nature has to teach us
Protein encapsulation is a growing area of interest, particularly in the fields of food science
and medicine. The sequestration of protein cargoes is achieved using a variety of methods …
and medicine. The sequestration of protein cargoes is achieved using a variety of methods …
Designing electrostatic interactions via polyelectrolyte monomer sequence
Charged polymers are ubiquitous in biological systems because electrostatic interactions
can drive complicated structure formation and respond to environmental parameters such as …
can drive complicated structure formation and respond to environmental parameters such as …
Prebiotically-relevant low polyion multivalency can improve functionality of membraneless compartments
Multivalent polyions can undergo complex coacervation, producing membraneless
compartments that accumulate ribozymes and enhance catalysis, and offering a mechanism …
compartments that accumulate ribozymes and enhance catalysis, and offering a mechanism …