Biological applications of thiocarbohydrazones and their metal complexes: A perspective review

C Bonaccorso, T Marzo, D La Mendola - Pharmaceuticals, 2019 - mdpi.com
Although organic compounds account for more than 99% of currently approved clinical
drugs, the established clinical use of cisplatin in cancer or auranofin in rheumatoid arthritis …

Isatin dimers and their biological activities

YZ Zhang, HZ Du, HL Liu, QS He, Z Xu - Archiv der Pharmazie, 2020 - Wiley Online Library
Dimerization is a promising strategy to develop novel drug candidates that could extend the
biological spectrum, enhance the activity, overcome drug resistance, as well as improve …

New Pd (II) complexes of the bisthiocarbohydrazones derived from isatin and disubstituted salicylaldehydes: Synthesis, characterization, crystal structures and …

Y Kaya, A Erçağ, Y Zorlu, Y Demir, İ Gülçin - JBIC Journal of Biological …, 2022 - Springer
Abstract Pd (II) complexes (Pd1, Pd2, and Pd3) were synthesized for the first time using
asymmetric isatin bisthiocarbohydrazone ligands and PdCl2 (PPh3) 2. All complexes were …

Preparation, antioxidant activity, and theoretical studies on the relationship between antioxidant and electronic properties of bis (thio/carbohydrazone) derivatives

H Muğlu, BZ Kurt, F Sönmez, E Güzel, MS Çavuş… - Journal of Physics and …, 2022 - Elsevier
A series of novel bis (thio/carbohydrazone) compounds has been prepared from
(thio)/carbohydrazide and various aldehyde derivatives. FTIR, 1 H and 13 C NMR …

Schiff bases based on thio/carbohydrazide: Synthesis, spectroscopic characterization, DFT, antimicrobial, DNA interactions and cytotoxicity studies

MS Çavuş, H Yakan, C Başkan, H Muğlu… - Journal of Molecular …, 2024 - Elsevier
Abstract New Schiff bases (1–8) have been prepared from numerous aldehydes and
thio/carbohydrazide. The chemical structures of these compounds were characterized using …

A new series of asymmetric bis-isatin derivatives containing urea/thiourea moiety: Preparation, spectroscopic elucidation, antioxidant properties and theoretical …

H Yakan, MS Cavuş, BZ Kurt, H Muğlu… - Journal of Molecular …, 2021 - Elsevier
In the present study, design, synthesis, characterization, and investigation of antioxidant
properties of novel asymmetric bis-isatin derivatives (1-8) containing urea/thiourea moiety …

Synthesis, characterization, quantum chemical calculations and antioxidant activity of new bis-isatin carbohydrazone and thiocarbohydrazone derivatives

H Muğlu, MS Çavuş, T Bakır, H Yakan - Journal of Molecular Structure, 2019 - Elsevier
Bis (5-chloro-2-oxoindolin-3-ylidene) thiocarbohydrazone (3), 1, 5-Bis (5-metoxy-2-
oxoindolin-3-ylidene) thiocarbohydrazone (4), 1, 5-Bis (5-metoxy-2-oxoindolin-3-ylidene) …

New β-isatin aldehyde-N,N′-thiocarbohydrazones: preparation, spectroscopic studies and DFT approach to antioxidant characteristics

H Yakan, TK Bakır, MS Çavuş, H Muğlu - Research on Chemical …, 2020 - Springer
Five new Schiff bases of isatin and its derivatives were prepared from
monothiocarbohydrazides and 5-chloro isatin. The chemical structures of the synthesized …

Synthesis, structure elucidation, antioxidant properties, and theoretical calculations of new Schiff bases–isatin derivatives

TK Bakır, MS Çavuş, H Muğlu, H Yakan - Research on Chemical …, 2024 - Springer
Isatin-derived Schiff bases are the subject of many studies, finding wide application areas in
polymer technology, pharmaceutical industry, and medicine. In this study, a series of new …

New Schiff bases based on isatin and (thio)/carbohydrazone: preparation, experimental–theoretical spectroscopic characterization, and DFT approach to antioxidant …

H Muğlu, F Sönmez, MS Çavuş, BZ Kurt… - Research on Chemical …, 2023 - Springer
In this study, synthesis, spectroscopic elucidation, and investigation of antioxidant properties
of new Schiff bases based on isatin and (thio)/carbohydrazone derivatives have been …