A tutorial on sobol'global sensitivity analysis applied to biological models

M Tosin, AMA Côrtes, A Cunha - Networks in Systems Biology …, 2020 - Springer
Nowadays, in addition to traditional qualitative methods, quantitative techniques are also a
standard tool to describe biological systems behavior. An example is the broad class of …

Multiple bifurcations of a discrete-time prey–predator model with mixed functional response

PA Naik, Z Eskandari, Z Avazzadeh… - International Journal of …, 2022 - World Scientific
In this paper, the one-and two-parameter bifurcations of a discrete-time prey–predator model
with a mixed functional response are investigated by computing their critical normal form …

Target site delivery and residence of nanomedicines: Application of quantitative systems pharmacology

JLS Au, RA Abbiati, MG Wientjes, Z Lu - Pharmacological reviews, 2019 - Elsevier
Quantitative systems pharmacology (QSP), an emerging field that entails using modeling
and computation to interpret, interrogate, and integrate drug effects spanning from the …

[HTML][HTML] Contact tracing–old models and new challenges

J Müller, M Kretzschmar - Infectious Disease Modelling, 2021 - Elsevier
Contact tracing is an effective method to control emerging infectious diseases. Since the
1980's, modellers are develo** a consistent theory for contact tracing, with the aim to find …

[書籍][B] Population dynamics: algebraic and probabilistic approach

UA Rozikov - 2020 - World Scientific
In this chapter we give some minimal preliminaries from biology, motivations of studying of
population dynamics, and define evolution operators and associated algebras related to free …

Testing, tracing and isolation in compartmental models

S Sturniolo, W Waites, T Colbourn… - PLoS computational …, 2021 - journals.plos.org
Existing compartmental mathematical modelling methods for epidemics, such as SEIR
models, cannot accurately represent effects of contact tracing. This makes them …

Harnessing potential COX-2 engagement for boosting anticancer activity of substituted 2-mercapto-4 (3H)-quinazolinones with promising EGFR/VEGFR-2 inhibitory …

A Hamdi, SS Tawfik, AR Ali, WA Ewes, A Haikal… - Bioorganic …, 2024 - Elsevier
We designed and synthesized new quinazolinone-tethered phenyl thiourea/thiadiazole
derivatives 4–26. Based on their structural characteristics, these compounds were proposed …

New approximations, and policy implications, from a delayed dynamic model of a fast pandemic

CP Vyasarayani, A Chatterjee - Physica D: Nonlinear Phenomena, 2020 - Elsevier
We study an SEIQR (Susceptible–Exposed–Infectious–Quarantined–Recovered) model due
to Young et al.(2019) for an infectious disease, with time delays for latency and an …

Consequences of delays and imperfect implementation of isolation in epidemic control

LS Young, S Ruschel, S Yanchuk, T Pereira - Scientific reports, 2019 - nature.com
For centuries isolation has been the main control strategy of unforeseen epidemic
outbreaks. When implemented in full and without delay, isolation is very effective. However …

[書籍][B] Cellular automata: analysis and applications

KP Hadeler, J Müller - 2017 - Springer
Early mathematics has been either “geometry”,“arithmetics”, or “algebra”, hence essentially
discrete. At the times of Newton and Leibnitz it was found that working with continua is, in …