Recent years have seen an increased understanding of the importance of myelination in
healthy brain function and neuropsychiatric diseases. Non-invasive microstructural magnetic …

There has been growing interest in brain aging and rejuvenation. It is well known that brain
aging is one of the leading causes of neurodegenerative diseases, such as Alzheimer's …

Several MRI measures have been proposed as in vivo biomarkers of myelin, each with
applications ranging from plasticity to pathology. Despite the availability of these myelin …

There is a pressing need for disease-modifying therapies in patients suffering from
neurodegenerative diseases, including Parkinson's disease (PD). However, these disorders …

Huntington's disease is an autosomal, dominantly inherited neurodegenerative disease
caused by an expansion of the CAG repeats in exon 1 of the huntingtin gene. Neuronal …

Amyloid-beta (Aβ) plays an important role in the pathogenesis of Alzheimer's disease.
Aberrant Aβ accumulation induces neuroinflammation, cerebrovascular alterations, and …

Studies of healthy brain aging traditionally report diffusivity patterns associated with white
matter degeneration using diffusion tensor imaging (DTI), which assumes that diffusion …

Despite the clear importance of language in our life, our vital ability to quickly and effectively
learn new words and meanings is neurobiologically poorly understood. Conventional …

Introduction Neurite orientation dispersion and density imaging (NODDI), a multi‐
compartment diffusion‐weighted imaging (DWI) model, may be useful for detecting early …

Extracellular β-amyloid (Aβ) plaque deposits and inflammatory immune activation are
thought to alter various aspects of tissue microstructure, such as extracellular free water …