The development of liver fibrosis primarily determines quality of life as well as prognosis.
Animal models are often used to model and understand the underlying mechanisms of …

The event of mutations in the surface antigen gene of hepatitis B virus (HBV) results in
undetectable hepatitis B surface antigen with positive/negative anti-hepatitis B core (anti …

The long-lasting persistence of HBV genomes in the liver (and in some cases also in the
serum) of HBsAg negative subjects is termed occult HBV infection (OBI). This peculiar …

Hepatitis B virus (HBV) reactivation occurs as a major complication of immunosuppressive
therapy among persons who have recovered from acute hepatitis and those who have …

Smoothened (SMO) belongs to the Hedgehog (HH) signaling pathway, which regulates cell
growth, migration, invasion and stem cells in cancer. The HH signaling pathway includes …

Chronic hepatitis B virus (HBV) infection is still a major health problem worldwide. Recently,
a great number of genetic studies based on single nucleotide polymorphisms (SNPs) and …

Occult hepatitis B virus (HBV) infection (OBI) refers to the presence of HBV DNA in the
absence of detectable hepatitis B surface antigen. Since OBI was first described in the late …

Background Occult hepatitis B virus infection (OBI) characterized by the absence of
detectable HBsAg remains a potential threat in blood safety. We investigated the actual …

Occult hepatitis B infection (OBI) is a status of undetectable serum hepatitis B surface
antigen (HBsAg) yet detectable serum and/or intrahepatic hepatitis B virus (HBV) DNA …

Chronic liver diseases (CLDs) such as hepatitis, alcoholic liver disease, nonalcoholic fatty
liver, and their downstream effect cancer affect more than a billion of people around the …