Viral infection induces inflammatory signals that coordinate YAP regulation of dysplastic cells in lung alveoli

X Lin, W Chen, G Yang, J Zhang, H Wang, Z Liu… - The Journal of Clinical …, 2024 - jci.org
Severe viral pneumonia can induce rapid expansion of KRT5+ basal-like cells in small
airways and alveoli; this forms a scar-like structure that persists in the injured alveoli and …

Macrophages and pulmonary fibrosis: a bibliometric and visual analysis of publications from 1990 to 2023

Y Min, L Wu, C Xu, W Han, Z Yin, X Pan, L Sun… - Frontiers in …, 2024 - frontiersin.org
Background The role of macrophages in the symptomatic and structural progression of
pulmonary fibrosis (PF) has garnered significant scholarly attention in recent years. This …

Comparative single-cell analysis reveals IFN-γ as a driver of respiratory sequelae post COVID-19

C Li, W Qian, X Wei, H Narasimhan, Y Wu, M Arish… - bioRxiv, 2023 - biorxiv.org
Post-acute sequelae of SARS-CoV-2 infection (PASC) represents an urgent public health
challenge, with its impact resonating in over 60 million individuals globally. While a growing …

Lung-resident lymphocytes and their roles in respiratory infections and chronic respiratory diseases

CA Sen, S Jie - Chinese Medical Journal Pulmonary and Critical …, 2024 - mednexus.org
Recent scientific breakthroughs have blurred traditional boundaries between innate and
adaptive immunity, revealing a sophisticated network of tissue-resident cells that deliver …

[HTML][HTML] Progress and Gaps in Respiratory Disease Research and Treatment: Highlights of the IRM 2024 in Shanghai

JS Zhang, Q Dhlamini, Q Guo, M Quan… - Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
Respiratory diseases pose a major public health challenge globally, necessitating
collaborative efforts between basic researchers and clinicians for effective solutions. China …

Lung epithelial progenitor-mediated release of TGF-β regulates induction and persistence of lung CD8+ TRM cells following mucosal BCG vaccination

JA Blake, J Seifert, R Ruscher, PR Giacomin… - bioRxiv, 2024 - biorxiv.org
A principal reason for the high global morbidity and mortality of tuberculosis (TB) is the lack
of efficacy of the only licensed TB vaccine, Bacillus Calmette-Guerin (BCG), as parenteral …