Hookworm infection

A Loukas, PJ Hotez, D Diemert… - Nature reviews Disease …, 2016 - nature.com
Hookworms are soil-transmitted nematode parasites that can reside for many years in the
small intestine of their human hosts; Necator americanus is the predominant infecting …

Cross-domain and viral interactions in the microbiome

AD Rowan-Nash, BJ Korry, E Mylonakis… - … and Molecular Biology …, 2019 - journals.asm.org
The importance of the microbiome to human health is increasingly recognized and has
become a major focus of recent research. However, much of the work has focused on a few …

Harnessing helminth-driven immunoregulation in the search for novel therapeutic modalities

SM Ryan, RM Eichenberger, R Ruscher… - PLoS …, 2020 - journals.plos.org
Parasitic helminths have coevolved with humans over millennia, intricately refining and
develo** an array of mechanisms to suppress or skew the host's immune system, thereby …

[HTML][HTML] The impact of a helminth-modified microbiome on host immunity

TP Brosschot, LA Reynolds - Mucosal immunology, 2018 - Elsevier
Intestinal helminths have well-characterized modulatory effects on mammalian immune
pathways. Ongoing helminth infection has been associated with both the suppression of …

Pathogens, microbiome and the host: emergence of the ecological Koch's postulates

P Vonaesch, M Anderson… - FEMS microbiology …, 2018 - academic.oup.com
Even though tremendous progress has been made in the last decades to elucidate the
mechanisms of intestinal homeostasis, dysbiosis and disease, we are only at the beginning …

Hatching of parasitic nematode eggs: a crucial step determining infection

TT Mkandawire, RK Grencis, M Berriman… - Trends in …, 2022 - cell.com
Although hatching from eggs is fundamental for nematode biology it remains poorly
understood. For animal-parasitic nematodes in particular, advancement has been slow …

Gut protozoa: friends or foes of the human gut microbiota?

M Chabé, A Lokmer, L Ségurel - Trends in Parasitology, 2017 - cell.com
The importance of the gut microbiota for human health has sparked a strong interest in the
study of the factors that shape its composition and diversity. Despite the growing evidence …

Evolving therapy for celiac disease

S Yoosuf, GK Makharia - Frontiers in pediatrics, 2019 - frontiersin.org
Gluten is known to be the main triggering factor for celiac disease (CeD), an immune-
mediated disorder. CeD is therefore managed using a strict and lifelong gluten-free diet …

Infections by human gastrointestinal helminths are associated with changes in faecal microbiota diversity and composition

TP Jenkins, Y Rathnayaka, PK Perera, LE Peachey… - PloS one, 2017 - journals.plos.org
Investigations of the impact that patent infections by soil-transmitted gastrointestinal
nematode parasites exert on the composition of the host gut commensal flora are attracting …

This gut ain't big enough for both of us. Or is it? Helminth–microbiota interactions in veterinary species

LE Peachey, TP Jenkins, C Cantacessi - Trends in parasitology, 2017 - cell.com
Gastrointestinal helminth parasites share their habitat with a myriad of other organisms, that
is, the commensal microbiota. Increasing evidence, particularly in humans and rodent …