Improved drug loading and antibacterial activity of minocycline-loaded PLGA nanoparticles prepared by solid/oil/water ion pairing method

TSJ Kashi, S Eskandarion… - International journal …, 2012 - Taylor & Francis
Background Low drug entrapment efficiency of hydrophilic drugs into poly (lactic-co-glycolic
acid)(PLGA) nanoparticles is a major drawback. The objective of this work was to investigate …

Nanocarrier possibilities for functional targeting of bioactive peptides and proteins: state-of-the-art

CG Moutinho, CM Matos, JA Teixeira… - Journal of drug …, 2012 - Taylor & Francis
This review attempts to provide an updated compilation of studies reported in the literature
pertaining to production of nanocarriers encasing peptides and/or proteins, in a way that …

Design of polymeric nanoparticles and its applications as drug delivery systems for acne treatment

CP Reis, N Martinho, C Rosado… - Drug development …, 2014 - Taylor & Francis
Objective: The aim of this study was to evaluate a formulation made of poly (lactide-co-
glycolide)(PLGA) nanoparticles containing azelaic acid for potential acne treatment …

Optimizing the process parameters for encapsulation of linamarin into PLGA nanoparticles using double emulsion solvent evaporation technique

AS Hussein, N Abdullah… - Advances in Polymer …, 2013 - Wiley Online Library
Linamarin‐loaded poly (lactide‐co‐glycolide)(PLGA) nanoparticles were prepared by using
a double emulsion solvent evaporation method using polyvinyl alcohol as a surfactant. A two …

Effect of surfactant on the preparation and characterization of gemcitabine-loaded particles

JH Lim, YG Na, HK Lee, SJ Kim, HJ Lee… - Journal of …, 2019 - Springer
Gemcitabine is used in the treatment of several solid tumors as one of anticancer nucleoside
analogues and is necessary to administer high doses to achieve the desired therapeutic …

Chemical stability enhancement and cytotoxicity reduction of papain loaded in PLGA nanospheres

C Chankhampan, J Manosroi… - Journal of …, 2014 - Taylor & Francis
Poly (lactic-co-glycolic acid)(PLGA) nanospheres loaded with papain were prepared by the
emulsion solvent diffusion in water (ESD) and the w/o/w emulsion solvent evaporation (ESE) …

Preparation and evaluation of polymeric microparticulates for improving cellular uptake of gemcitabine

JH Lim, SK You, JS Baek, CJ Hwang… - International Journal …, 2012 - Taylor & Francis
Background Gemcitabine must be administered at high doses to elicit the required
therapeutic response because of its very short plasma half-life due to rapid metabolism …

Mucoadhesive interaction of cysteine grafted poly (2-hydroxyethyl aspartamide) with pig mucin layer of surface plasmon resonance biosensor

HW Park, JD Kim - Journal of Industrial and Engineering Chemistry, 2009 - Elsevier
A new type of thiolated polyaspartamide was synthesized and characterized with a surface
plasmon resonance (SPR) biosensor. l-Cysteine grafted poly (2-hydroxyethyl …

Therapeutic effect of chitosan modification on salmon-calcitonin-loaded PLGA nanoparticles

MJ Lee, DY Seo, HE Lee, GJ Choi - Korean Journal of Chemical …, 2011 - Springer
Although salmon-calcitonin (sCT) has been known as a potent drug for the treatment of
osteoporosis, its oral dosage form products have not been commercially available primarily …

Preparation of poly-lactic acid nano/microparticles using supercritical anti-solvent with enhanced mass transfer

SJ Park, SH Choi, HH Yoon - Journal of Industrial and Engineering …, 2010 - Elsevier
Supercritical anti-solvent precipitation with enhanced mass transfer (SAS-EM) was applied
for the production of micro and sub-microparticles of poly-lactic acid (PLA). SAS-EM …