Benefits and harms of 'smart drugs'(nootropics) in healthy individuals
F Schifano, V Catalani, S Sharif, F Napoletano… - Drugs, 2022 - Springer
Abstract 'Smart drugs'(also known as 'nootropics' and 'cognitive enhancers'[CEs]) are being
used by healthy subjects (ie students and workers) typically to improve memory, attention …
used by healthy subjects (ie students and workers) typically to improve memory, attention …
Modafinil for cognitive neuroenhancement in healthy non-sleep-deprived subjects: a systematic review
Modafinil is an FDA-approved eugeroic that directly increases cortical catecholamine levels,
indirectly upregulates cerebral serotonin, glutamate, orexin, and histamine levels, and …
indirectly upregulates cerebral serotonin, glutamate, orexin, and histamine levels, and …
[HTML][HTML] Cognitive function in a randomized trial of evolocumab
RP Giugliano, F Mach, K Zavitz, C Kurtz… - … England Journal of …, 2017 - Mass Medical Soc
Background Findings from clinical trials of proprotein convertase subtilisin–kexin type 9
(PCSK9) inhibitors have led to concern that these drugs or the low levels of low-density …
(PCSK9) inhibitors have led to concern that these drugs or the low levels of low-density …
Direct comparison of the acute subjective, emotional, autonomic, and endocrine effects of MDMA, methylphenidate, and modafinil in healthy subjects
Abstract Rationale 3, 4-Methylenedioxymethamphetamine (MDMA) is used recreationally
and investigated as an adjunct to psychotherapy. Methylphenidate and modafinil are …
and investigated as an adjunct to psychotherapy. Methylphenidate and modafinil are …
The impact of neuroscience on society: cognitive enhancement in neuropsychiatric disorders and in healthy people
In addition to causing distress and disability to the individual, neuropsychiatric disorders are
also extremely expensive to society and governments. These disorders are both common …
also extremely expensive to society and governments. These disorders are both common …
Modafinil augmentation therapy in unipolar and bipolar depression: a systematic review and meta-analysis of randomized controlled trials
Objective: Current pharmacologic treatments for a depressive episode in unipolar major
depressive disorder (MDD) and bipolar depression are limited by low rates of remission …
depressive disorder (MDD) and bipolar depression are limited by low rates of remission …
The neurobiology of modafinil as an enhancer of cognitive performance and a potential treatment for substance use disorders
Rationale and objectives Modafinil (MOD) and its R-enantiomer (R-MOD) are approved
medications for narcolepsy and other sleep disorders. They have also been used, off-label …
medications for narcolepsy and other sleep disorders. They have also been used, off-label …
How effective are pharmaceuticals for cognitive enhancement in healthy adults? A series of meta-analyses of cognitive performance during acute administration of …
Modafinil, methyphenidate (MPH) and d-amphetamine (d-amph) are putative cognitive
enhancers. However, efficacy of cognitive enhancement has yet to be fully established. We …
enhancers. However, efficacy of cognitive enhancement has yet to be fully established. We …
Develo** treatments for cognitive deficits in schizophrenia: the challenge of translation
Schizophrenia is a life-long debilitating mental disorder affecting tens of millions of people
worldwide. The serendipitous discovery of antipsychotics focused pharmaceutical research …
worldwide. The serendipitous discovery of antipsychotics focused pharmaceutical research …
Is neuroenhancement by noninvasive brain stimulation a net zero-sum proposition?
In the past several years, the number of studies investigating enhancement of cognitive
functions through noninvasive brain stimulation (NBS) has increased considerably. NBS …
functions through noninvasive brain stimulation (NBS) has increased considerably. NBS …