[HTML][HTML] The physiological, biochemical, and molecular roles of zinc transporters in zinc homeostasis and metabolism

T Kambe, T Tsuji, A Hashimoto… - Physiological …, 2015 - journals.physiology.org
Zinc is involved in a variety of biological processes, as a structural, catalytic, and intracellular
and intercellular signaling component. Thus zinc homeostasis is tightly controlled at the …

Zinc signals and immunity

M Maywald, I Wessels, L Rink - International journal of molecular sciences, 2017 - mdpi.com
Zinc homeostasis is crucial for an adequate function of the immune system. Zinc deficiency
as well as zinc excess result in severe disturbances in immune cell numbers and activities …

Zinc and the immune system

L Rink - Proceedings of the Nutrition Society, 2000 - cambridge.org
Zn is an essential trace element for all organisms. In human subjects body growth and
development is strictly dependent on Zn. The nervous, reproductive and immune systems …

The role of zinc in selective neuronal death after transient global cerebral ischemia

JY Koh, SW Suh, BJ Gwag, YY He, CY Hsu, DW Choi - Science, 1996 - science.org
Zinc is present in presynaptic nerve terminals throughout the mammalian central nervous
system and likely serves as an endogenous signaling substance. However, excessive …

Zinc signals and immune function

H Haase, L Rink - Biofactors, 2014 - Wiley Online Library
For more than 50 years, it has been known that zinc deficiency compromises immune
function. During this time, knowledge about the biochemistry of zinc has continued to grow …

Functions of zinc in signaling, proliferation and differentiation of mammalian cells

D Beyersmann, H Haase - Biometals, 2001 - Springer
Zinc is essential for cell proliferation and differentiation, especially for the regulation of DNA
synthesis and mitosis. On the molecular level, it is a structural constituent of a great number …

The function and regulation of zinc in the brain

RF Krall, T Tzounopoulos, E Aizenman - Neuroscience, 2021 - Elsevier
Nearly sixty years ago Fredrich Timm developed a histochemical technique that revealed a
rich reserve of free zinc in distinct regions of the brain. Subsequent electron microscopy …

Zinc metabolism in the brain: relevance to human neurodegenerative disorders

MP Cuajungco, GJ Lees - Neurobiology of disease, 1997 - Elsevier
Zinc is an important trace element in biology. An important pool of zinc in the brain is the one
present in synaptic vesicles in a subgroup of glutamatergic neurons. In this form it can be …

Zinc and brain injury

DW Choi, JY Koh - Annual review of neuroscience, 1998 - annualreviews.org
▪ Abstract Zinc is an essential catalytic or structural element of many proteins, and a
signaling messenger that is released by neural activity at many central excitatory synapses …

Zinc deficiency and immune function.

CL Keen, ME Gershwin - Annual review of nutrition, 1990 - europepmc.org
Zn deficiency can have marked effects on virtually all components of the immune system.
That these effects can be functionally significant is demonstrated by the increased …