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Signalling pathways in autism spectrum disorder: mechanisms and therapeutic implications
CC Jiang, LS Lin, S Long, XY Ke, K Fukunaga… - Signal transduction and …, 2022 - nature.com
Autism spectrum disorder (ASD) is a prevalent and complex neurodevelopmental disorder
which has strong genetic basis. Despite the rapidly rising incidence of autism, little is known …
which has strong genetic basis. Despite the rapidly rising incidence of autism, little is known …
Autism spectrum disorder: neuropathology and animal models
Autism spectrum disorder (ASD) has a major impact on the development and social
integration of affected individuals and is the most heritable of psychiatric disorders. An …
integration of affected individuals and is the most heritable of psychiatric disorders. An …
Advancing the understanding of autism disease mechanisms through genetics
Progress in understanding the genetic etiology of autism spectrum disorders (ASD) has
fueled remarkable advances in our understanding of its potential neurobiological …
fueled remarkable advances in our understanding of its potential neurobiological …
Inhibition in the amygdala anxiety circuitry
O Babaev, C Piletti Chatain… - Experimental & molecular …, 2018 - nature.com
Inhibitory neurotransmission plays a key role in anxiety disorders, as evidenced by the
anxiolytic effect of the benzodiazepine class of γ-aminobutyric acid (GABA) receptor …
anxiolytic effect of the benzodiazepine class of γ-aminobutyric acid (GABA) receptor …
Reconsidering animal models used to study autism spectrum disorder: Current state and optimizing future
Neurodevelopmental disorders (NDDs), including autism spectrum disorder (ASD) and
intellectual disability (ID), are pervasive, often lifelong disorders, lacking evidence‐based …
intellectual disability (ID), are pervasive, often lifelong disorders, lacking evidence‐based …
Prefrontal cortex and social cognition in mouse and man
Social cognition is a complex process that requires the integration of a wide variety of
behaviors, including salience, reward-seeking, motivation, knowledge of self and others …
behaviors, including salience, reward-seeking, motivation, knowledge of self and others …
A standardized social preference protocol for measuring social deficits in mouse models of autism
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by social
communication deficits and other behavioral abnormalities. The three-chamber social …
communication deficits and other behavioral abnormalities. The three-chamber social …
Common mechanisms of excitatory and inhibitory imbalance in schizophrenia and autism spectrum disorders
R Gao, P Penzes - Current molecular medicine, 2015 - ingentaconnect.com
Autism Spectrum Disorders (ASD) and Schizophrenia (SCZ) are cognitive disorders with
complex genetic architectures but overlap** behavioral phenotypes, which suggests …
complex genetic architectures but overlap** behavioral phenotypes, which suggests …
Interneuron dysfunction in psychiatric disorders
O Marín - Nature Reviews Neuroscience, 2012 - nature.com
Schizophrenia, autism and intellectual disabilities are best understood as spectrums of
diseases that have broad sets of causes. However, it is becoming evident that these …
diseases that have broad sets of causes. However, it is becoming evident that these …
Animal models of neuropsychiatric disorders
Modeling of human neuropsychiatric disorders in animals is extremely challenging given the
subjective nature of many symptoms, the lack of biomarkers and objective diagnostic tests …
subjective nature of many symptoms, the lack of biomarkers and objective diagnostic tests …