Ulcerative colitis in adults: A review
Importance Ulcerative colitis (UC) is a chronic inflammatory condition of the colon, with a
prevalence exceeding 400 per 100 000 in North America. Individuals with UC have a lower …
prevalence exceeding 400 per 100 000 in North America. Individuals with UC have a lower …
The JAK/STAT signaling pathway: from bench to clinic
X Hu, J Li, M Fu, X Zhao, W Wang - Signal transduction and targeted …, 2021 - nature.com
The Janus kinase/signal transducer and activator of transcription (JAK/STAT) signaling
pathway was discovered more than a quarter-century ago. As a fulcrum of many vital cellular …
pathway was discovered more than a quarter-century ago. As a fulcrum of many vital cellular …
ECCO guidelines on therapeutics in ulcerative colitis: medical treatment
Ulcerative colitis [UC] is a chronic inflammatory bowel disease [IBD] characterised by colonic
inflammation extending to a variable extent from the rectum. Care of the patient with UC …
inflammation extending to a variable extent from the rectum. Care of the patient with UC …
Efficacy and safety of biologics and small molecule drugs for patients with moderate-to-severe ulcerative colitis: a systematic review and network meta-analysis
Background There is a growing armamentarium for the treatment of moderate-to-severe
ulcerative colitis. We aimed to compare the relative efficacy and safety of biologics and small …
ulcerative colitis. We aimed to compare the relative efficacy and safety of biologics and small …
ECCO guidelines on the prevention, diagnosis, and management of infections in inflammatory bowel disease
T Kucharzik, P Ellul, T Greuter, JF Rahier… - Journal of Crohn's …, 2021 - academic.oup.com
The introduction and broad use of new immunosuppressive agents, including biologic
agents and JAK inhibitors, have revolutionised treatment of inflammatory bowel disease …
agents and JAK inhibitors, have revolutionised treatment of inflammatory bowel disease …
Safety profile of upadacitinib over 15 000 patient-years across rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis and atopic dermatitis
GR Burmester, SB Cohen, KL Winthrop, P Nash… - RMD open, 2023 - rmdopen.bmj.com
Objective To evaluate the long-term safety profile for upadacitinib across rheumatoid arthritis
(RA), psoriatic arthritis (PsA), ankylosing spondylitis (AS) and atopic dermatitis (AD) …
(RA), psoriatic arthritis (PsA), ankylosing spondylitis (AS) and atopic dermatitis (AD) …
Filgotinib versus placebo or adalimumab in patients with rheumatoid arthritis and inadequate response to methotrexate: a phase III randomised clinical trial
Objective To evaluate the efficacy and safety of the Janus kinase-1-preferential inhibitor
filgotinib versus placebo or tumour necrosis factor-α inhibitor therapy in patients with active …
filgotinib versus placebo or tumour necrosis factor-α inhibitor therapy in patients with active …
International consensus on the prevention of venous and arterial thrombotic events in patients with inflammatory bowel disease
Patients with inflammatory bowel disease (IBD) are at increased risk of thrombotic events.
Therapies for IBD have the potential to modulate this risk. The aims of this Evidence-Based …
Therapies for IBD have the potential to modulate this risk. The aims of this Evidence-Based …
ECCO guidelines on inflammatory bowel disease and malignancies
This guideline is the second European Crohn's and Colitis Organisation [ECCO] evidence-
based consensus on inflammatory bowel disease [IBD] and malignancy, and is an update …
based consensus on inflammatory bowel disease [IBD] and malignancy, and is an update …
Versatile carbon dots with superoxide dismutase-like nanozyme activity and red fluorescence for inflammatory bowel disease therapeutics
Y Ma, J Zhao, L Cheng, C Li, X Yan, Z Deng, Y Zhang… - Carbon, 2023 - Elsevier
Inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn's disease
(CD), is a chronic and recurrent disease that seriously affects the life quality of patients …
(CD), is a chronic and recurrent disease that seriously affects the life quality of patients …