From patterns to patients: Advances in clinical machine learning for cancer diagnosis, prognosis, and treatment

K Swanson, E Wu, A Zhang, AA Alizadeh, J Zou - Cell, 2023 - cell.com
Machine learning (ML) is increasingly used in clinical oncology to diagnose cancers, predict
patient outcomes, and inform treatment planning. Here, we review recent applications of ML …

Artificial intelligence for digital and computational pathology

AH Song, G Jaume, DFK Williamson, MY Lu… - Nature Reviews …, 2023 - nature.com
Advances in digitizing tissue slides and the fast-paced progress in artificial intelligence,
including deep learning, have boosted the field of computational pathology. This field holds …

Towards a general-purpose foundation model for computational pathology

RJ Chen, T Ding, MY Lu, DFK Williamson, G Jaume… - Nature Medicine, 2024 - nature.com
Quantitative evaluation of tissue images is crucial for computational pathology (CPath) tasks,
requiring the objective characterization of histopathological entities from whole-slide images …

A visual-language foundation model for computational pathology

MY Lu, B Chen, DFK Williamson, RJ Chen, I Liang… - Nature Medicine, 2024 - nature.com
The accelerated adoption of digital pathology and advances in deep learning have enabled
the development of robust models for various pathology tasks across a diverse array of …

A multimodal generative AI copilot for human pathology

MY Lu, B Chen, DFK Williamson, RJ Chen, M Zhao… - Nature, 2024 - nature.com
Computational pathology, has witnessed considerable progress in the development of both
task-specific predictive models and task-agnostic self-supervised vision encoders …

Artificial intelligence in histopathology: enhancing cancer research and clinical oncology

A Shmatko, N Ghaffari Laleh, M Gerstung, JN Kather - Nature cancer, 2022 - nature.com
Artificial intelligence (AI) methods have multiplied our capabilities to extract quantitative
information from digital histopathology images. AI is expected to reduce workload for human …

Artificial intelligence for diagnosis and Gleason grading of prostate cancer: the PANDA challenge

W Bulten, K Kartasalo, PHC Chen, P Ström… - Nature medicine, 2022 - nature.com
Artificial intelligence (AI) has shown promise for diagnosing prostate cancer in biopsies.
However, results have been limited to individual studies, lacking validation in multinational …

Visual language pretrained multiple instance zero-shot transfer for histopathology images

MY Lu, B Chen, A Zhang… - Proceedings of the …, 2023 - openaccess.thecvf.com
Contrastive visual language pretraining has emerged as a powerful method for either
training new language-aware image encoders or augmenting existing pretrained models …

The 2022 World Health Organization classification of tumors of the urinary system and male genital organs—part B: prostate and urinary tract tumors

GJ Netto, MB Amin, DM Berney, EM Compérat, AJ Gill… - European urology, 2022 - Elsevier
Abstract The 2022 World Health Organization (WHO) classification of the urinary and male
genital tumors was recently published by the International Agency for Research on Cancer …

Prediction of tumor origin in cancers of unknown primary origin with cytology-based deep learning

F Tian, D Liu, N Wei, Q Fu, L Sun, W Liu, X Sui… - Nature Medicine, 2024 - nature.com
Cancer of unknown primary (CUP) site poses diagnostic challenges due to its elusive
nature. Many cases of CUP manifest as pleural and peritoneal serous effusions. Leveraging …