Superior gene transfection efficiency in triple negative breast cancer by RAFT-mediated amino acid-based cationic diblock copolymers

R Saha, S Haldar, SS Pradhan, K Jana… - Journal of Materials …, 2023 - pubs.rsc.org
To date, the synthesis of efficient and safe gene carriers with low toxicity and appreciable
gene transfection efficiency has been the major hurdle associated with non-viral gene …

Micellar drug delivery vehicles formed from amphiphilic block copolymers bearing photo-cross-linkable cyclopentenone side groups

J Stouten, N Sijstermans, J Babilotte, A Pich… - Polymer …, 2022 - pubs.rsc.org
Amphiphilic block copolymers are of specific interest in the field of nanomedicine, and are
used to encapsulate hydrophobic drugs for targeted drug delivery. To improve micellar …

Membrane-Active Thermoresponsive Block Copolymers Containing a Diacylglycerol-Based Segment: RAFT Synthesis, Doxorubicin Encapsulation, and Evaluation of …

I Kurowska, KH Markiewicz… - …, 2023 - ACS Publications
Herein, we report the formation of drug delivery systems from original thermoresponsive
block copolymers containing lipid-based segments. Two acrylate monomers derived from …

Development of Supramolecules in the Field of Nanomedicines

AK Mehata, MS Muthu - Pharmaceutical applications of supramolecules, 2023 - Springer
Nanomedicine is a rapidly expanding field that uses nanomaterials of novel chemical,
physical, and biological features to diagnose and treat the diseases. Supramolecules are …

Tailoring Amphiphilic Copolymers for Improved Aqueous Foam Stability

LC Brown, KM Hinnant, GC Daniels, PE Sudol… - Langmuir, 2023 - ACS Publications
Amphiphilic copolymers of various-molecular-weight (MW) poly (ethylene glycol)(PEG) were
synthesized via reversible addition–fragmentation chain transfer (RAFT) polymerization. The …

Surface Eroding Methacrylic Anhydride Copolymers and Model Drug Release

AL Santefort, AC Appolon, LJ Cowart… - … Chemistry and Physics, 2023 - Wiley Online Library
Methacrylic anhydride (MAA)‐based copolymers are synthesized to probe how comonomer
composition and type affect the erosion profiles. Anhydrides readily undergo hydrolysis …