Abnormal enzymatic activities are directly related to the development of cancers. Identifying
the location and expression levels of these enzymes in live cancer cells have considerable …

Traditional biochemical methods for enzyme detection are mainly based on antibody-based
immunoassays, which lack the ability to monitor the spatiotemporal distribution and, in …

Fibroblast activation protein (FAP) is a cell-surface serine protease that acts on various
hormones and extracellular matrix components. FAP is highly upregulated in a wide variety …

Conspectus Enzymes are a class of important substances for life, and their abnormal levels
are associated with many diseases. Thus, great progress has been made in the past decade …

Proteases are excellent biomarkers for a variety of diseases, offer multiple opportunities for
diagnostic applications and are valuable targets for therapy. From a chemistry-based …

Cytochrome P450 2J2 (CYP2J2), a key enzyme responsible for oxidative metabolism of
various xenobiotics and endogenous compounds, participates in a diverse array of …

The identification of contributing factors leading to the development of Colorectal Cancer
(CRC), as the third fatal malignancy, is crucial. Today, the tumor microenvironment has been …

Photoswitchable fluorescent nanomaterials have received much attention due to their
versatile applications but they normally do not show high-contrast red fluorescence. Herein …

Near-infrared (NIR) fluorescent probes possess a characteristic molecular structure with a
highly conjugated polyene or polynuclear system, thus exhibiting a long emission …

Inflammation is a significant protective response in biological systems and associated with
various diseases. Peroxynitrite (ONOO−) as a highly active oxidant participates in the …