The occurrence of the novel severe acute respiratory syndrome coronavirus-2 (SARS-CoV-
2), responsible for coronavirus disease 2019 (COVD-19), represents a catastrophic threat to …

Hepatocyte resident afflictions continue to affect the human population unabated. The
asialoglycoprotein receptor (ASGPR) is primarily expressed on hepatocytes and minimally …

CRISPR-Cas9 screens are powerful tools for high-throughput interrogation of genome
function, but can be confounded by nuclease-induced toxicity at both on-and off-target sites …

Glycosylation is catalyzed by various glycosyltransferase enzymes which are mostly located
in the Golgi apparatus in cells. These enzymes glycosylate various complex carbohydrates …

Aberrant glycosylation is a key feature of malignant transformation. Hypersialylation, the
enhanced expression of sialic acid-terminated glycoconjugates on the cell surface, has …

Breast milk is an unbeatable food that covers all the nutritional requirements of an infant in
its different stages of growth up to six months after birth. In addition, breastfeeding benefits …

Chemical tools have accelerated progress in glycoscience, reducing experimental barriers
to studying protein glycosylation, the most widespread and complex form of posttranslational …

Interleukin-1 is a cytokine with potent inflammatory and immune-amplifying effects, mainly
produced by macrophages during defensive reactions. In mammals, IL-1 is a superfamily of …

Although their central role is in the prevention of bleeding, platelets probably contribute to
diverse processes that extend beyond hemostasis and thrombosis. For example, platelets …

C-type lectins (CTLs) represent the most complex family of animal/human lectins that
comprises 17 different groups. During evolution, CTLs have developed by diversification to …