Clinical implications of preterm infant gut microbiome development

DB Healy, CA Ryan, RP Ross, C Stanton… - Nature …, 2022 - nature.com
Perturbations to the infant gut microbiome during the first weeks to months of life affect
growth, development and health. In particular, assembly of an altered intestinal microbiota …

Advances in droplet digital polymerase chain reaction on microfluidic chips

D Xu, W Zhang, H Li, N Li, JM Lin - Lab on a Chip, 2023 - pubs.rsc.org
The PCR technique has been known to the general public since the pandemic outbreak of
COVID-19. This technique has progressed through three stages: from simple PCR to real …

Stunted microbiota and opportunistic pathogen colonization in caesarean-section birth

Y Shao, SC Forster, E Tsaliki, K Vervier, A Strang… - Nature, 2019 - nature.com
Immediately after birth, newborn babies experience rapid colonization by microorganisms
from their mothers and the surrounding environment. Diseases in childhood and later in life …

Gut pathogen colonization precedes bloodstream infection in the neonatal intensive care unit

DJ Schwartz, N Shalon, K Wardenburg… - Science translational …, 2023 - science.org
Bacterial bloodstream infections (BSIs) resulting in late-onset sepsis affect up to half of
extremely preterm infants and have substantial morbidity and mortality. Bacterial species …

Rapid MinION profiling of preterm microbiota and antimicrobial-resistant pathogens

RM Leggett, C Alcon-Giner, D Heavens, S Caim… - Nature …, 2020 - nature.com
The MinION sequencing platform offers near real-time analysis of DNA sequence; this
makes the tool attractive for deployment in fieldwork or clinical settings. We used the MinION …

Building upon current knowledge and techniques of indoor microbiology to construct the next era of theory into microorganisms, health, and the built environment

PF Horve, S Lloyd, GA Mhuireach, L Dietz… - Journal of exposure …, 2020 - nature.com
In the constructed habitat in which we spend up to 90% of our time, architectural design
influences occupants' behavioral patterns, interactions with objects, surfaces, rituals, the …

Effects of probiotics in preterm infants: a network meta-analysis

C Chi, C Li, N Buys, W Wang, C Yin, J Sun - Pediatrics, 2021 - publications.aap.org
OBJECTIVE: To compare probiotic supplements for premature infants. DATA SOURCES: We
searched PubMed, Embase, Cochrane, and ProQuest from inception of these databases to …

The indoors microbiome and human health

JA Gilbert, EM Hartmann - Nature Reviews Microbiology, 2024 - nature.com
Indoor environments serve as habitat for humans and are replete with various reservoirs and
niches for microorganisms. Microorganisms enter indoor spaces with their human and non …

Clinical sequelae of gut microbiome development and disruption in hospitalized preterm infants

R Thänert, DJ Schwartz, EC Keen, C Hall-Moore… - Cell host & …, 2024 - cell.com
Aberrant preterm infant gut microbiota assembly predisposes to early-life disorders and
persistent health problems. Here, we characterize gut microbiome dynamics over the first 3 …

Connection between gut microbiome and brain development in preterm infants

J Lu, EC Claud - Developmental psychobiology, 2019 - Wiley Online Library
Dysbiosis of the gut microbiome in preterm infants predisposes the neonate to various major
morbidities including neonatal necrotizing enterocolitis and sepsis in the neonatal intensive …