The limitations of traditional cancer treatments are driving the creation and development of
new nanomedicines. At present, with the rapid increase of research on nanomedicine in the …

The macrophage is a key cell in the pro-and anti-inflammatory response including that of the
inflammatory microenvironment of malignant tumors. Much current drug development in …

Sex differences have been well identified in many brain tumors. Even though glioblastoma
(GBM) is the most common primary malignant brain tumor in adults and has the worst …

Introduction The immunosuppressive tumor microenvironment (TME) is a major barrier to the
efficacy of chimeric antigen receptor T cells (CAR-T cells) in glioblastoma (GBM). Transgenic …

Antigen presentation machinery and professional antigen-presenting cells (APCs) are
fundamental for an efficacious immune response against cancers, especially in the context …