High-quality chromosome-scale haplotype sequences of diploid genomes, polyploid
genomes, and metagenomes provide important insights into genetic variation associated …

Despite the great progress made in the understanding of the biological behavior of certain
types of invasive breast cancer, there is still no single histological or molecular classification …

Circulating tumor cells (CTCs) derived from primary tumors and/or metastatic tumors are
markers for tumor prognosis, and can also be used to monitor therapeutic efficacy and tumor …

Chromosomal instability (CIN), defined by variations in the number or structure of
chromosomes from cell to cell, is recognized as a distinctive characteristic of cancer …

Chromosomal instability (CIN) is an important marker of cancer, which is closely related to
tumorigenesis, disease progression, treatment efficacy, and patient prognosis. However …

The aim of the study was to evaluate the impact of the updated 2018 American Society of
Clinical Oncology (ASCO)/College of American Pathologists (CAP) guideline on human …

Simple Summary Molecular subty** and therapeutic target identification in osteosarcoma
have been extremely challenging due to the high degree of heterogeneity in its genetic …

Breast cancer is the most prevalent neoplasm in women. ER+ (Luminal subtype),
representing over 70% of breast tumors, is a genetically diverse group. Structural and …

Background Chromosomal instability (CIN) is a defining characteristic of cancer and is part
of the genetic instability of cancer. CIN results in both numeric alterations of chromosomes …

Somatic copy number alterations (SCNAs) in tumors are clinically significant diagnostic,
prognostic, and predictive biomarkers. SCNA detection from targeted next-generation …