Cancer is one of the leading causes of death globally. The development of drug resistance
is the main contributor to cancer-related mortality. Cancer cells exploit multiple mechanisms …

The risk assessment of chemical carcinogens is one major task in toxicology. Even though
exposure has been mitigated effectively during the last decades, low levels of carcinogenic …

Observational data have shown that some cancer survivors develop chronic conditions like
frailty, sarcopenia, cardiac dysfunction, and mild cognitive impairment earlier and/or at a …

Despite much progress in the diagnosis and treatment of cancer, tumour diseases constitute
one of the main reasons of deaths worldwide. The side effects of chemotherapy and drug …

Abstract Purpose of Review This review aims to summarize epidemiological literature
published between May 15, 2018, and May 14, 2019, that examines the relationship …

Several epidemiological and experimental studies have demonstrated that many human
diseases are not only caused by specific genetic and environmental factors but also by gene …

Breast cancer is the fifth most common cause of cancer death in the world and the second
most common fatal cancer in women. Epidemiological studies and clinical data have …

The comet assay or single cell gel electrophoresis, is the most common method used to
measure strand breaks and a variety of other DNA lesions in human populations. To …

Carcinogenesis is a multistage process that involves a series of events comprising of
genetic and epigenetic changes leading to the initiation, promotion and progression of …

γH2AX has emerged in the last 20 years as a central player in the DDR (DNA damage
response), with specificity for DSBs (double-strand breaks). Upon the generation of DSBs, γ …