Advanced glycation end-products (AGEs): Formation, chemistry, classification, receptors, and diseases related to AGEs

A Twarda-Clapa, A Olczak, AM Białkowska… - Cells, 2022 - mdpi.com
Advanced glycation end-products (AGEs) constitute a non-homogenous, chemically diverse
group of compounds formed either exogeneously or endogeneously on the course of …

[HTML][HTML] Molecular mechanisms and therapeutic targets for diabetic kidney disease

KR Tuttle, R Agarwal, CE Alpers, GL Bakris… - Kidney international, 2022 - Elsevier
Diabetic kidney disease has a high global disease burden and substantially increases the
risk of kidney failure and cardiovascular events. Despite treatment, there is substantial …

AGE/RAGE in diabetic kidney disease and ageing kidney

XQ Wu, DD Zhang, YN Wang, YQ Tan, XY Yu… - Free Radical Biology …, 2021 - Elsevier
Diabetic kidney disease (DKD) is the primary cause of chronic kidney disease that inevitably
progress to end-stage kidney disease. Intervention strategies such as blood glucose control …

Research advances of advanced glycation end products in milk and dairy products: Formation, determination, control strategy and immunometabolism via gut …

L Dong, Y Li, Q Chen, Y Liu, Z Qiao, S Sang, J Zhang… - Food Chemistry, 2023 - Elsevier
Advanced glycosylation end products (AGEs) are a series of complex compounds which
generate in the advanced phase of Maillard reaction, which can pose a non-negligible risk …

Advanced glycation end products and diabetes mellitus: mechanisms and perspectives

M Khalid, G Petroianu, A Adem - Biomolecules, 2022 - mdpi.com
Persistent hyperglycemic state in type 2 diabetes mellitus leads to the initiation and
progression of non-enzymatic glycation reaction with proteins and lipids and nucleic acids …

Dietary advanced glycation end‐products: Perspectives linking food processing with health implications

Q Zhang, Y Wang, L Fu - … Reviews in Food Science and Food …, 2020 - Wiley Online Library
Dietary advanced glycation end products (dAGEs) are complex and heterogeneous
compounds derived from nonenzymatic glycation reactions during industrial processing and …

Dissecting Maillard reaction production in fried foods: Formation mechanisms, sensory characteristic attribution, control strategy, and gut homeostasis regulation

B Shi, X Guo, H Liu, K Jiang, L Liu, N Yan, MA Farag… - Food Chemistry, 2024 - Elsevier
Foods rich in carbohydrates or fats undergo the Maillard reaction during frying, which
promotes the color, flavor and sensory characteristics formation. In the meanwhile, Maillard …

Inflammation and premature ageing in chronic kidney disease

T Ebert, SC Pawelzik, A Witasp, S Arefin, S Hobson… - Toxins, 2020 - mdpi.com
Persistent low-grade inflammation and premature ageing are hallmarks of the uremic
phenotype and contribute to impaired health status, reduced quality of life, and premature …

Advanced glycation end products (AGEs) may be a striking link between modern diet and health

V Gill, V Kumar, K Singh, A Kumar, JJ Kim - Biomolecules, 2019 - mdpi.com
The Maillard reaction is a simple but ubiquitous reaction that occurs both in vivo and ex vivo
during the cooking or processing of foods under high-temperature conditions, such as …

The role of dietary advanced glycation end products in metabolic dysfunction

D Sergi, H Boulestin, FM Campbell… - Molecular Nutrition & …, 2021 - Wiley Online Library
Advanced glycation end products (AGEs) are a heterogeneous group of molecules
produced, non‐enzymatically, from the interaction between reducing sugars and the free …