[HTML][HTML] Bioactive substances of cyanobacteria and microalgae: Sources, metabolism, and anticancer mechanism insights

A Bouyahya, S Bakrim, I Chamkhi, D Taha… - Biomedicine & …, 2024 - Elsevier
Cyanobacteria and microalgae contain various phytochemicals, including bioactive
components in the form of secondary metabolites, namely flavonoids, phenolic acids …

[HTML][HTML] Microalgae in modern cancer therapy: Current knowledge

ME Abd El-Hack, S Abdelnour, M Alagawany… - Biomedicine & …, 2019 - Elsevier
Cancer is an everyday medical concern which requires an appropriate treatment strategy.
The malfunction of cell cycle is a well-established cause for cancer induction. Chemotherapy …

A comprehensive review of the therapeutic potential of cyanobacterial marine bioactives: Unveiling the hidden treasures of the sea

T Nawaz, L Gu, S Fahad, S Saud, Z Jiang… - Food and Energy …, 2023 - Wiley Online Library
Marine cyanobacterial bioactives, due to their diverse chemistry and promising
pharmacological properties, hold significant potential as therapeutic agents. Here, we …

[HTML][HTML] Marine cyanobacteria and microalgae metabolites—A rich source of potential anticancer drugs

A Mondal, S Bose, S Banerjee, JK Patra, J Malik… - Marine Drugs, 2020 - mdpi.com
Cancer is at present one of the utmost deadly diseases worldwide. Past efforts in cancer
research have focused on natural medicinal products. Over the past decades, a great deal of …

Autophagic flux disruption contributes to Ganoderma lucidum polysaccharide-induced apoptosis in human colorectal cancer cells via MAPK/ERK activation

H Pan, Y Wang, K Na, Y Wang, L Wang, Z Li… - Cell death & …, 2019 - nature.com
Targeting autophagy may serve as a promising strategy for cancer therapy. Ganoderma
lucidum polysaccharide (GLP) has been shown to exert promising anti-cancer effects …

Integration of high-content screening and untargeted metabolomics for comprehensive functional annotation of natural product libraries

KL Kurita, E Glassey, RG Linington - … of the National Academy of Sciences, 2015 - pnas.org
Traditional natural products discovery using a combination of live/dead screening followed
by iterative bioassay-guided fractionation affords no information about compound structure …

Bacteria and bacterial anticancer agents as a promising alternative for cancer therapeutics

P Baindara, SM Mandal - Biochimie, 2020 - Elsevier
Cancer is the leading cause of deaths worldwide, though significant advances have
occurred in its diagnosis and treatment. The development of resistance against …

[HTML][HTML] Marine cyanobacteria as sources of lead anticancer compounds: a review of families of metabolites with cytotoxic, antiproliferative, and antineoplastic effects

B Robles-Bañuelos, LM Durán-Riveroll… - Molecules, 2022 - mdpi.com
The marine environment is highly diverse, each living creature fighting to establish and
proliferate. Among marine organisms, cyanobacteria are astounding secondary metabolite …

Natural small-molecule enhancers of autophagy induce autophagic cell death in apoptosis-defective cells

BYK Law, WK Chan, SW Xu, JR Wang, LP Bai, L Liu… - Scientific reports, 2014 - nature.com
Resistance of cancer cells to chemotherapy is a significant problem in oncology and the
development of sensitising agents or small-molecules with new mechanisms of action to kill …

[HTML][HTML] New drugs from the sea: Pro-apoptotic activity of sponges and algae derived compounds

G Ercolano, P De Cicco, A Ianaro - Marine Drugs, 2019 - mdpi.com
Natural compounds derived from marine organisms exhibit a wide variety of biological
activities. Over the last decades, a great interest has been focused on the anti-tumour role of …