Cellular mechanisms that regulate the interplay of synaptic excitation and inhibition are
thought to be central to the functional stability of healthy neuronal circuits. A growing body of …

Fluorescence imaging techniques play a pivotal role in our understanding of the nervous
system. The emergence of various super-resolution microscopy methods and specialized …

The balance between excitatory and inhibitory (E and I) synapses is thought to be critical for
information processing in neural circuits. However, little is known about the spatial principles …

The concepts called STED/RESOLFT superresolve features by a light-driven transfer of
closely packed molecules between two different states, typically a nonfluorescent “off” state …

Inhibitory synapses mediate the majority of synaptic inhibition in the brain, thereby
controlling neuronal excitability, firing, and plasticity. Although essential for neuronal …

The molecular composition of presynaptic and postsynaptic neuronal terminals is dynamic,
and yet long-term stabilizations in postsynaptic responses are necessary for synaptic …

NMDA receptors (NMDARs) play key roles in the use-dependent adaptation of glutamatergic
synapses underpinning memory formation. In the forebrain, these plastic processes involve …

Synaptic plasticity is a critical process that regulates neuronal activity by allowing neurons to
adjust their synaptic strength in response to changes in activity. Despite the high proximity of …

GABAA receptors (GABAAR) are the major players in fast inhibitory neurotransmission in the
central nervous system (CNS). Regulation of GABAAR trafficking and the control of their …

Abstract Information processing in the brain depends on specialized organization of
neurotransmitter receptors and scaffolding proteins within the postsynaptic density …