Overlap** genes in natural and engineered genomes

BW Wright, MP Molloy, PR Jaschke - Nature Reviews Genetics, 2022 - nature.com
Modern genome-scale methods that identify new genes, such as proteogenomics and
ribosome profiling, have revealed, to the surprise of many, that overlap in genes, open …

[HTML][HTML] Pathogenesis of endometriosis: the genetic/epigenetic theory

PR Koninckx, A Ussia, L Adamyan, A Wattiez… - Fertility and sterility, 2019 - Elsevier
Objective To study the pathophysiology of endometriosis. Design Overview of observations
on endometriosis. Setting Not applicable. Patient (s) None. Interventions (s) None. Main …

Evolutionary pathways and trajectories in antibiotic resistance

F Baquero, JL Martinez, V F. Lanza… - Clinical Microbiology …, 2021 - Am Soc Microbiol
Evolution is the hallmark of life. Descriptions of the evolution of microorganisms have
provided a wealth of information, but knowledge regarding “what happened” has precluded …

Robustness of cellular functions

J Stelling, U Sauer, Z Szallasi, FJ Doyle, J Doyle - Cell, 2004 - cell.com
Robustness, the ability to maintain performance in the face of perturbations and uncertainty,
is a long-recognized key property of living systems. Owing to intimate links to cellular …

Perspective: evolution and detection of genetic robustness

JAGM De Visser, J Hermisson, GP Wagner… - …, 2003 - Wiley Online Library
Robustness is the invariance of phenotypes in the face of perturbation. The robustness of
phenotypes appears at various levels of biological organization, including gene expression …

The juvenile hormones

WG Goodman, M Cusson - Insect endocrinology, 2012 - Elsevier
Publisher Summary This chapter discusses the juvenile hormones (JH). The JH, a family of
acyclic sesquiterpenoids, are essential to insect development and reproduction. This …

Adaptive value of high mutation rates of RNA viruses: separating causes from consequences

SF Elena, R Sanjuán - Journal of virology, 2005 - Am Soc Microbiol
As a consequence of the lack of proofreading activity of RNA virus polymerases, new viral
genetic variants are constantly created. RNA viruses readily adapt to changing …

Developmental bias predicts 60 million years of wing shape evolution

PT Rohner, D Berger - … of the National Academy of Sciences, 2023 - National Acad Sciences
The degree to which developmental biases affect trait evolution is subject to much debate.
Here, we first quantify fluctuating asymmetry as a measure of developmental variability, ie …

Mutational robustness can facilitate adaptation

JA Draghi, TL Parsons, GP Wagner, JB Plotkin - Nature, 2010 - nature.com
Robustness seems to be the opposite of evolvability. If phenotypes are robust against
mutation, we might expect that a population will have difficulty adapting to an environmental …

Evolution of giant pandoravirus revealed by CRISPR/Cas9

H Bisio, M Legendre, C Giry, N Philippe… - Nature …, 2023 - nature.com
Giant viruses (GVs) are a hotspot of unresolved controversies since their discovery,
including the definition of “Virus” and their origin. While increasing knowledge of genome …