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Artificial intelligence in bulk and single-cell RNA-sequencing data to foster precision oncology
M Del Giudice, S Peirone, S Perrone, F Priante… - International journal of …, 2021 - mdpi.com
Artificial intelligence, or the discipline of develo** computational algorithms able to
perform tasks that requires human intelligence, offers the opportunity to improve our idea …
perform tasks that requires human intelligence, offers the opportunity to improve our idea …
eXplainable Artificial Intelligence (XAI) for the identification of biologically relevant gene expression patterns in longitudinal human studies, insights from obesity …
A Anguita-Ruiz, A Segura-Delgado… - PLoS computational …, 2020 - journals.plos.org
Until date, several machine learning approaches have been proposed for the dynamic
modeling of temporal omics data. Although they have yielded impressive results in terms of …
modeling of temporal omics data. Although they have yielded impressive results in terms of …
Inheritances and wealth inequality: a machine learning approach
This paper explores the relationship between received inheritances and the distribution of
wealth (financial, non-financial and total) in four developed countries: the United States …
wealth (financial, non-financial and total) in four developed countries: the United States …
[HTML][HTML] Knowledge generation with rule induction in cancer omics
The explosion of omics data availability in cancer research has boosted the knowledge of
the molecular basis of cancer, although the strategies for its definitive resolution are still not …
the molecular basis of cancer, although the strategies for its definitive resolution are still not …
LogicGep: Boolean networks inference using symbolic regression from time-series transcriptomic profiling data
Reconstructing the topology of gene regulatory network from gene expression data has
been extensively studied. With the abundance functional transcriptomic data available, it is …
been extensively studied. With the abundance functional transcriptomic data available, it is …
A probabilistic graphical model for system-wide analysis of gene regulatory networks
Motivation The inference of gene regulatory networks (GRNs) from DNA microarray
measurements forms a core element of systems biology-based phenoty**. In the recent …
measurements forms a core element of systems biology-based phenoty**. In the recent …
Network-driven cancer cell avatars for combination discovery and biomarker identification for DNA damage response inhibitors
O Papp, V Jordán, S Hetey, R Balázs… - npj Systems Biology …, 2024 - nature.com
Combination therapy is well established as a key intervention strategy for cancer treatment,
with the potential to overcome monotherapy resistance and deliver a more durable efficacy …
with the potential to overcome monotherapy resistance and deliver a more durable efficacy …
Mining high average-utility sequential rules to identify high-utility gene expression sequences in longitudinal human studies
High-utility sequential pattern mining techniques have demonstrated good performance in
identifying associations between mRNA levels in microarray experiments taking into account …
identifying associations between mRNA levels in microarray experiments taking into account …
[HTML][HTML] Identification of cancer related genes using feature selection and association rule mining
High throughput sequencing generates large volumes of high dimensional data. Identifying
informative features from the generated big data is always a challenge. Feature selection …
informative features from the generated big data is always a challenge. Feature selection …
MinePath: mining for phenotype differential sub-paths in molecular pathways
Pathway analysis methodologies couple traditional gene expression analysis with
knowledge encoded in established molecular pathway networks, offering a promising …
knowledge encoded in established molecular pathway networks, offering a promising …