Artificial biocatalytic linear cascades for preparation of organic molecules
The review compiles artificial cascades involving enzymes with a focus on the last 10 years.
A cascade is defined as the combination of at least two reaction steps in a single reaction …
A cascade is defined as the combination of at least two reaction steps in a single reaction …
Biocatalytic oxidation reactions: a chemist's perspective
JJ Dong, E Fernández‐Fueyo… - Angewandte Chemie …, 2018 - Wiley Online Library
Oxidation chemistry using enzymes is approaching maturity and practical applicability in
organic synthesis. Oxidoreductases (enzymes catalysing redox reactions) enable chemists …
organic synthesis. Oxidoreductases (enzymes catalysing redox reactions) enable chemists …
RetroBioCat as a computer-aided synthesis planning tool for biocatalytic reactions and cascades
As the enzyme toolbox for biocatalysis has expanded, so has the potential for the
construction of powerful enzymatic cascades for efficient and selective synthesis of target …
construction of powerful enzymatic cascades for efficient and selective synthesis of target …
[HTML][HTML] Enzymes revolutionize the bioproduction of value-added compounds: From enzyme discovery to special applications
Competitive sustainable production in industry demands new and better biocatalysts,
optimized bioprocesses and cost-effective product recovery. Our review sheds light on the …
optimized bioprocesses and cost-effective product recovery. Our review sheds light on the …
Alcohol dehydrogenases as catalysts in organic synthesis
Alcohol dehydrogenases (ADHs) have become important catalysts for stereoselective
oxidation and reduction reactions of alcohols, aldehydes and ketones. The aim of this …
oxidation and reduction reactions of alcohols, aldehydes and ketones. The aim of this …
Predicting enzymatic reactions with a molecular transformer
The use of enzymes for organic synthesis allows for simplified, more economical and
selective synthetic routes not accessible to conventional reagents. However, predicting …
selective synthetic routes not accessible to conventional reagents. However, predicting …
Whole‐cell cascade biotransformations for one‐pot multistep organic synthesis
S Wu, Z Li - ChemCatChem, 2018 - Wiley Online Library
Performing one‐pot multi‐catalysis reactions is a revolutionary tool for multistep synthesis,
representing a fast‐develo** theme in catalysis field. To develop cascade reactions …
representing a fast‐develo** theme in catalysis field. To develop cascade reactions …
Baeyer-Villiger oxidations: biotechnological approach
Abstract Baeyer-Villiger monooxygenases (BVMOs) are a very well-known and intensively
studied class of flavin-dependent enzymes. Their substrate promiscuity, high chemo-, regio …
studied class of flavin-dependent enzymes. Their substrate promiscuity, high chemo-, regio …
Photobiocatalytic Oxyfunctionalization with High Reaction Rate using a Baeyer–Villiger Monooxygenase from Burkholderia xenovorans in Metabolically Engineered …
Baeyer–Villiger monooxygenases (BVMOs) catalyze the oxidation of ketones to lactones
under very mild reaction conditions. This enzymatic route is hindered by the requirement of a …
under very mild reaction conditions. This enzymatic route is hindered by the requirement of a …
Recent advances in enzymatic oxidation of alcohols
J Liu, S Wu, Z Li - Current opinion in chemical biology, 2018 - Elsevier
Highlights•Discovery of new Cu 2+ radical oxidases with high activity and broad substrate
range.•Development of computational tool for engineering cofactor preference of alcohol …
range.•Development of computational tool for engineering cofactor preference of alcohol …