The role of fibroblast growth factor 23 in inflammation and anemia

B Czaya, C Faul - International journal of molecular sciences, 2019 - mdpi.com
In patients with chronic kidney disease (CKD), adverse outcomes such as systemic
inflammation and anemia are contributing pathologies which increase the risks for …

MMP-2 and its implications on cardiac function and structure: interplay with inflammation in hypertension

TR Vitorino, AF do Prado, SB de Assis Cau… - Biochemical …, 2023 - Elsevier
Hypertension is one of the leading risk factors for the development of heart failure. Despite
being a multifactorial disease, in recent years, preclinical and clinical studies suggest strong …

Increased arterial stiffness in resistant hypertension is associated with inflammatory biomarkers

NR Barbaro, V Fontana, R Modolo, AP De Faria… - Blood …, 2015 - Taylor & Francis
Background. Increased levels of inflammatory biomarkers such as interleukin-6 (IL-6), 10 (IL-
10), 1β (IL-1β), tumor necrosis factor-α (TNF-α) high-sensitivity C-reactive protein (hs-CRP) …

ADAM17, a key player of cardiac inflammation and fibrosis in heart failure development during chronic catecholamine stress

J Adu-Amankwaah, GK Adzika, AO Adekunle… - Frontiers in Cell and …, 2021 - frontiersin.org
Heart failure development is characterized by persistent inflammation and progressive
fibrosis owing to chronic catecholamine stress. In a chronic stress state, elevated …

Experimental and human evidence for lipocalin‐2 (neutrophil gelatinase‐associated lipocalin [NGAL]) in the development of cardiac hypertrophy and heart failure

FZ Marques, PR Prestes, SG Byars… - Journal of the …, 2017 - Am Heart Assoc
Background Cardiac hypertrophy increases the risk of develo** heart failure and
cardiovascular death. The neutrophil inflammatory protein, lipocalin‐2 (LCN 2/NGAL), is …

Association between inflammation and cardiac geometry in chronic kidney disease: findings from the CRIC study

J Gupta, EA Dominic, JC Fink, AO Ojo, IR Barrows… - PLoS …, 2015 - journals.plos.org
Background Left ventricular hypertrophy (LVH) and myocardial contractile dysfunction are
independent predictors of mortality in patients with chronic kidney disease (CKD). The …

Increased neutrophil to lymphocyte ratio in patients with resistant hypertension

E Belen, A Sungur, MA Sungur… - The Journal of Clinical …, 2015 - Wiley Online Library
Resistant hypertension (RHT) is an important disease that causes an increase in
cardiovascular risk, yet its etiology remains unclear. The authors aimed to investigate …

Hypertension, inflammation and atrial fibrillation

F Angeli, G Reboldi, P Verdecchia - Journal of hypertension, 2014 - journals.lww.com
Atrial fibrillation is the most common cardiac arrhyth-mia in clinical practice and is a major
risk factor for stroke and mortality [1]. It affects approximately 1–2% of the general …

Microalbuminuria in patients with essential hypertension and its relationship to target organ damage: an Indian experience

B Hitha, JM Pappachan, HB Pillai… - Saudi Journal of …, 2008 - journals.lww.com
Persistent microalbuminuria (MA) is the earliest indicator of chronic kidney disease (CKD) in
patients with diabetes mellitus and hypertension. Patients with MA have high risk for target …

Urinary albumin excretion is associated with true resistant hypertension

A Oliveras, P Armario, R Hernández-Del Rey… - Journal of human …, 2010 - nature.com
Resistant (or refractory) hypertension (RH) is a clinical diagnosis based on blood pressure
(BP) office measurements. About one third of subjects with suspected RH have indeed …