The use of plant secondary metabolites has gained considerable attention among clinicians
in the prevention and treatment of cancer. A secondary metabolite isolated mainly from the …

Podophyllotoxin, along with its various derivatives and congeners are widely recognized as
broad-spectrum pharmacologically active compounds. Etoposide, for instance, is the …

The aryltetralin-type lignan podophyllotoxin, the main agent present in the resin extracted
from the rhizomes of different podophyllum species, possesses important antineoplastic and …

Abstract Thymus lotocephalus G. Lopez & R. Morales is an aromatic species endemic to the
south of Portugal with medicinal properties. The aim of this work was to evaluate the effect of …

Adverse effects and drug resistance to the current onchopharmacologicals have increased
the demand for alternative novel therapeutics. We herein introduce justicidin B, an …

The present paper discusses the use of monolayers of lipid mixtures mimicking the
composition of biological membranes of bacteria, erythrocyte and yeast in the context of the …

The genus Artemisia has been utilized worldwide due to its immense potential for protection
against various diseases, especially malaria. Artemisia absinthium, previously renowned for …

Phenolic acids are an important group of plant secondary metabolites with various, valuable
therapeutic properties. Apart from plants growing in the open air, tissue cultures can be an …

Abstract Treatment options for most cancers are still insufficient, despite developments and
technology advancements. It has been postulated that the immune response to progressive …

Griffithsin (GRFT), a lectin from Griffithsia species, inhibits human immunodeficiency virus-1
(HIV-1) replication at sub-nanomolar concentrations, with limited cellular toxicity. However …