Proteomics-Based identification of dysregulated proteins and biomarker discovery in invasive ductal carcinoma, the most common breast cancer subtype

AN Neagu, D Whitham, L Seymour, N Haaker, I Pelkey… - Proteomes, 2023 - mdpi.com
Invasive ductal carcinoma (IDC) is the most common histological subtype of malignant
breast cancer (BC), and accounts for 70–80% of all invasive BCs. IDC demonstrates great …

Progression from ductal carcinoma in situ to invasive breast cancer: molecular features and clinical significance

J Wang, B Li, M Luo, J Huang, K Zhang… - … and Targeted Therapy, 2024 - nature.com
Ductal carcinoma in situ (DCIS) represents pre-invasive breast carcinoma. In untreated
cases, 25–60% DCIS progress to invasive ductal carcinoma (IDC). The challenge lies in …

High-dose paclitaxel and its combination with CSF1R inhibitor in polymeric micelles for chemoimmunotherapy of triple negative breast cancer

C Lim, D Hwang, M Yazdimamaghani, HM Atkins… - Nano Today, 2023 - Elsevier
The presence of immunosuppressive immune cells in tumors is a significant barrier to the
generation of therapeutic immune responses. Similarly, in vivo triple-negative breast cancer …

[HTML][HTML] MIND the translational gap: Preclinical models of ductal carcinoma in situ

SJ Hutten, J Jonkers - Clinical and Translational Medicine, 2023 - ncbi.nlm.nih.gov
Ductal carcinoma in situ (DCIS) is a non-invasive premalignant lesion and is considered a
non-obligate precursor of invasive breast cancer (IBC). DCIS has increasingly been …

Modeling intratumor heterogeneity in breast cancer

E McDonough, M Barroso, F Ginty, DT Corr - Biofabrication, 2024 - iopscience.iop.org
Reduced therapy response in breast cancer has been correlated with heterogeneity in
biomarker composition, expression level, and spatial distribution of cancer cells within a …

Trichinella spiralis Larval Extract as a Biological Anti‐Tumor Therapy in a Murine Model of Ehrlich Solid Carcinoma

SS Younis, AM Salama, DA Elmehy… - Parasite …, 2024 - Wiley Online Library
Trichinella spiralis (T. spiralis) is an immunomodulating parasite that can adversely affect
tumor growth and extend host lifespan. The aim of this study was to elucidate the …

The Pretenders: Basal Breast Cancer Cells Mimic Epidermal Keratinocytes and Rely on Retinoic Acid Signaling for Survival, Invasion and Metastasis

AE Doak - 2024 - search.proquest.com
In breast cancer, the presence of cells expressing basal epithelial markers is associated with
a high risk of tumor invasion, metastasis and therapy resistance. It has therefore been …

Clinicopathological features of breast cancer progression: From DCIS to invasive ductal carcinoma

J Zhang, N Aishan, BA SAAD, Y Chen, J Zhou, F Ji… - 2023 - researchsquare.com
Purpose Ductal carcinoma in situ (DCIS) is regarded as non-invasive precursor lesion of
invasive ductal carcinoma (IDC) but the molecular mechanisms and tumorigenesis behind …