The pathogenesis of ischemic stroke is complex, and PI3K/Akt signaling is considered to
play a crucial role in it. The PI3K/Akt pathway regulates inflammation, oxidative stress …

ABSTRACT GLP-1 (Glucagon-like peptide 1) serves as both a peptide hormone and a
growth factor, is released upon nutrient intake and contributes to insulin secretion stimulated …

Parkinson's disease (PD) is the second most common progressive age-related
neurodegenerative disorder. Paramount evidence shed light on the role of PI3K/AKT …

Abstract L-3, 4-dihydroxyphenylalanine (L-DOPA) is currently the preferred treatment for
Parkinson's Disease (PD) and is considered the gold standard. However, prolonged use of L …

Parkinson's disease (PD) is the second most common neurodegenerative disease
worldwide, and current treatment options are unsatisfactory on the long term. Several …

ABSTRACT Introduction Protein kinase B (Akt), an essential protein in the PI3K/Akt/mTOR
signaling pathway, plays a crucial role in tumor progression. Over the past two years …

Ischemic stroke (IS), predominantly triggered by blockages in cerebral blood flow, is
increasingly recognized as a critical public health issue. The combination of Salvia …

Abstract β2-adrenoreceptors (β2AR have been identified recently as regulators of the α-
synuclein gene (SNCA), one of the key milieus endorsed in injury of dopamine neurons in …

The organophosphorus insecticide Chlorpyrifos (CPF) is widely used worldwide due to its
high effectiveness. However, when ingested through the mouth and nose, it can cause …

Recently, Parkinson's disease (PD) has become a remarkable burden on families and
society with an acceleration of population aging having several pathological hallmarks such …