Intracellular targeting mechanisms by antimicrobial peptides

CF Le, CM Fang, SD Sekaran - Antimicrobial agents and …, 2017 - journals.asm.org
Antimicrobial peptides (AMPs) are expressed in various living organisms as first-line host
defenses against potential harmful encounters in their surroundings. AMPs are short …

Alternative mechanisms of action of cationic antimicrobial peptides on bacteria

JDF Hale, REW Hancock - Expert review of anti-infective therapy, 2007 - Taylor & Francis
Cationic antimicrobial peptides are a novel type of antibiotic offering much potential in the
treatment of microbial-related diseases. They offer many advantages for commercial …

Antimicrobial peptides in animals and their role in host defences

KA Brogden, M Ackermann, PB McCray Jr… - International journal of …, 2003 - Elsevier
Domesticated animals have a large variety of antimicrobial peptides that serve as natural
innate barriers limiting microbial infection or, in some instances, act as an integral …

Structural determinants of host defense peptides for antimicrobial activity and target cell selectivity

D Takahashi, SK Shukla, O Prakash, G Zhang - Biochimie, 2010 - Elsevier
Antimicrobial host defense peptides (HDPs) are a critical component of the innate immunity
with microbicidal, endotoxin-neutralizing, and immunostimulatory properties. HDPs kill …

[HTML][HTML] Cutaneous injury induces the release of cathelicidin anti-microbial peptides active against group A Streptococcus

RA Dorschner, VK Pestonjamasp… - Journal of Investigative …, 2001 - Elsevier
Cathelicidins are a family of peptides thought to provide an innate defensive barrier against
a variety of potential microbial pathogens. The human and mouse cathelicidins (LL-37 and …

Cathelicidins-a family of multifunctional antimicrobial peptides

R Bals, JM Wilson - Cellular and Molecular Life Sciences CMLS, 2003 - Springer
One component of host defence at mucosal surfaces are epithelial-derived antimicrobial
peptides. Cathelicidins are one family of antimicrobial peptides characterized by conserved …

Identification of CRAMP, a cathelin-related antimicrobial peptide expressed in the embryonic and adult mouse

RL Gallo, KJ Kim, M Bernfield, CA Kozak… - Journal of Biological …, 1997 - jbc.org
Cathelicidins are the precursors of potent antimicrobial peptides that have been identified in
several mammalian species. Prior work has suggested that members of this gene family can …

Structural features and biological activities of the cathelicidin‐derived antimicrobial peptides

R Gennaro, M Zanetti - Peptide Science, 2000 - Wiley Online Library
Cathelicidins are a numerous group of mammalian proteins that carry diverse antimicrobial
peptides at the C‐terminus of a highly conserved preproregion. These peptides, which …

De novo generation of cationic antimicrobial peptides: influence of length and tryptophan substitution on antimicrobial activity

B Deslouches, SM Phadke, V Lazarevic… - Antimicrobial agents …, 2005 - journals.asm.org
Comparison of human immunodeficiency virus lentiviral lytic peptide 1 with other host-
derived peptides indicates that antimicrobial properties of membrane-active peptides are …

The porcine lung as a potential model for cystic fibrosis

CS Rogers, WM Abraham… - … of Physiology-Lung …, 2008 - journals.physiology.org
Airway disease currently causes most of the morbidity and mortality in patients with cystic
fibrosis (CF). However, understanding the pathogenesis of CF lung disease and develo** …