Molecular mechanisms of olfactory detection in insects: beyond receptors

HR Schmidt, R Benton - Open biology, 2020 - royalsocietypublishing.org
Insects thrive in diverse ecological niches in large part because of their highly sophisticated
olfactory systems. Over the last two decades, a major focus in the study of insect olfaction …

Drosophila sensory receptors—a set of molecular Swiss Army Knives

C Montell - Genetics, 2021 - academic.oup.com
Genetic approaches in the fruit fly, Drosophila melanogaster, have led to a major triumph in
the field of sensory biology—the discovery of multiple large families of sensory receptors …

Response of the microbiome–gut–brain axis in Drosophila to amino acid deficit

B Kim, MI Kanai, Y Oh, M Kyung, EK Kim, IH Jang… - Nature, 2021 - nature.com
A balanced intake of macronutrients—protein, carbohydrate and fat—is essential for the well-
being of organisms. An adequate calorific intake but with insufficient protein consumption …

Dietary L-Glu sensing by enteroendocrine cells adjusts food intake via modulating gut PYY/NPF secretion

J Gao, S Zhang, P Deng, Z Wu, B Lemaitre… - Nature …, 2024 - nature.com
Amino acid availability is monitored by animals to adapt to their nutritional environment.
Beyond gustatory receptors and systemic amino acid sensors, enteroendocrine cells (EECs) …

Sestrin mediates detection of and adaptation to low-leucine diets in Drosophila

X Gu, P Jouandin, PV Lalgudi, R Binari, ML Valenstein… - Nature, 2022 - nature.com
Mechanistic target of rapamycin complex 1 (mTORC1) regulates cell growth and metabolism
in response to multiple nutrients, including the essential amino acid leucine. Recent work in …

Evolutionary history of chemosensory-related gene families across the Arthropoda

S Eyun, HY Soh, M Posavi, JB Munro… - Molecular biology …, 2017 - academic.oup.com
Chemosensory-related gene (CRG) families have been studied extensively in insects, but
their evolutionary history across the Arthropoda had remained relatively unexplored. Here …

An expression atlas of variant ionotropic glutamate receptors identifies a molecular basis of carbonation sensing

JA Sánchez-Alcañiz, AF Silbering, V Croset… - Nature …, 2018 - nature.com
Through analysis of the Drosophila ionotropic receptors (IRs), a family of variant ionotropic
glutamate receptors, we reveal that most IRs are expressed in peripheral neuron …

Recent advances in the genetic basis of taste detection in Drosophila

YCD Chen, A Dahanukar - Cellular and Molecular Life Sciences, 2020 - Springer
The insect gustatory system senses taste information from environmental food substrates
and processes it to control feeding behaviors. Drosophila melanogaster has been a …

[HTML][HTML] Ionotropic receptors mediate Drosophila oviposition preference through sour gustatory receptor neurons

Y Chen, H Amrein - Current Biology, 2017 - cell.com
Carboxylic acids are present in many foods, being especially abundant in fruits. Yet,
relatively little is known about how acids are detected by gustatory systems and whether …

Functional architecture of reward learning in mushroom body extrinsic neurons of larval Drosophila

T Saumweber, A Rohwedder, M Schleyer… - Nature …, 2018 - nature.com
The brain adaptively integrates present sensory input, past experience, and options for
future action. The insect mushroom body exemplifies how a central brain structure brings …