Consolidation of implicit memory in the invertebrate Aplysia and explicit memory in the
mammalian hippocampus are associated with remodeling and growth of preexisting …

Receptor tyrosine kinases of the Eph family bind to cell surface-associated ephrin ligands on
neighboring cells. The ensuing bidirectional signals have emerged as a major form of …

Summary Expanded GGGGCC (G4C2) nucleotide repeats within the C9ORF72 gene are the
most common genetic mutation associated with both amyotrophic lateral sclerosis (ALS) and …

Experience results in long-lasting changes in dendritic spine size, yet how the molecular
architecture of the synapse responds to plasticity remains poorly understood. Here a …

Aberrant hexanucleotide repeat expansions in C9orf72 are the most common genetic
change underlying amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) …

Schizophrenia is an etiologically heterogeneous psychiatric disease, which exists in familial
and nonfamilial (sporadic) forms. Here, we examine the possibility that rare de novo copy …

Many cell adhesion molecules are localized at synaptic sites in neuronal axons and
dendrites. These molecules bridge pre-and postsynaptic specializations but do far more …

Chemical synapses are asymmetric intercellular junctions that mediate synaptic
transmission. Synaptic junctions are organized by trans-synaptic cell adhesion molecules …

We identify the leucine-rich repeat transmembrane protein LRRTM2 as a key regulator of
excitatory synapse development and function. LRRTM2 localizes to excitatory synapses in …

Cbln1, secreted from cerebellar granule cells, and the orphan glutamate receptor δ2
(GluD2), expressed by Purkinje cells, are essential for synapse integrity between these …