Mitochondrial DNA: more than an evolutionary bystander

JWO Ballard, N Pichaud - Functional Ecology, 2014 - Wiley Online Library
The vast majority of studies employing mt DNA in evolutionary biology and ecology have
used it as a means to infer demographic and historical patterns without pondering the …

A meta‐analysis of the strength and nature of cytoplasmic genetic effects

R Dobler, B Rogell, F Budar… - Journal of evolutionary …, 2014 - academic.oup.com
Genetic variation in cytoplasmic genomes (ie the mitochondrial genome in animals, and the
combined mitochondrial and chloroplast genomes in plants) was traditionally assumed to …

Positive and purifying selection in mitochondrial genomes of a bird with mitonuclear discordance

HE Morales, A Pavlova, L Joseph… - Molecular …, 2015 - Wiley Online Library
Diversifying selection on metabolic pathways can reduce intraspecific gene flow and
promote population divergence. An opportunity to explore this arises from mitonuclear …

Flexible thermal sensitivity of mitochondrial oxygen consumption and substrate oxidation in flying insect species

HA Menail, SB Cormier, M Ben Youssef… - Frontiers in …, 2022 - frontiersin.org
Mitochondria have been suggested to be paramount for temperature adaptation in insects.
Considering the large range of environments colonized by this taxon, we hypothesized that …

Mitochondrial DNA and temperature tolerance in lager yeasts

ECP Baker, D Peris, RV Moriarty, XC Li, JC Fay… - Science …, 2019 - science.org
A growing body of research suggests that the mitochondrial genome (mtDNA) is important
for temperature adaptation. In the yeast genus Saccharomyces, species have diverged in …

Mitochondria-encoded genes contribute to evolution of heat and cold tolerance in yeast

XC Li, D Peris, CT Hittinger, EA Sia, JC Fay - Science advances, 2019 - science.org
Genetic analysis of phenotypic differences between species is typically limited to interfertile
species. Here, we conducted a genome-wide noncomplementation screen to identify genes …

Inherited mitochondrial DNA variants can affect complement, inflammation and apoptosis pathways: insights into mitochondrial–nuclear interactions

MC Kenney, M Chwa, SR Atilano… - Human Molecular …, 2014 - academic.oup.com
Age-related macular degeneration (AMD) is the leading cause of vision loss in developed
countries. While linked to genetic polymorphisms in the complement pathway, there are …

Thermal acclimation and subspecies-specific effects on heart and brain mitochondrial performance in a eurythermal teleost (Fundulus heteroclitus)

DJ Chung, HJ Bryant… - Journal of Experimental …, 2017 - journals.biologists.com
Mitochondrial performance may play a role in setting whole-animal thermal tolerance limits
and their plasticity, but the relative roles of adjustments in mitochondrial performance across …

Dramatic changes in mitochondrial substrate use at critically high temperatures: a comparative study using Drosophila

LB Jørgensen, J Overgaard… - Journal of …, 2021 - journals.biologists.com
Ectotherm thermal tolerance is critical to species distribution, but at present the physiological
underpinnings of heat tolerance remain poorly understood. Mitochondrial function is …

Effects of temperature on complexes I and II mediated respiration, ROS generation and oxidative stress status in isolated gill mitochondria of the mud crab Scylla …

B Paital, GBN Chainy - Journal of Thermal Biology, 2014 - Elsevier
Abstract Effects of fluctuations in habitat temperature (18–30°) on mitochondrial respiratory
behavior and oxidative metabolic responses in the euryhaline ectotherm Scylla serrata are …