Bioactive synthetic polymers

K Jung, N Corrigan, EHH Wong, C Boyer - Advanced Materials, 2022 - Wiley Online Library
Synthetic polymers are omnipresent in society as textiles and packaging materials, in
construction and medicine, among many other important applications. Alternatively, natural …

[HTML][HTML] Antimicrobial polymeric materials with quaternary ammonium and phosphonium salts

Y Xue, H **ao, Y Zhang - International journal of molecular sciences, 2015 - mdpi.com
Polymeric materials containing quaternary ammonium and/or phosphonium salts have been
extensively studied and applied to a variety of antimicrobial-relevant areas. With various …

[HTML][HTML] Membrane-disruptive peptides/peptidomimetics-based therapeutics: Promising systems to combat bacteria and cancer in the drug-resistant era

L Lin, J Chi, Y Yan, R Luo, X Feng, Y Zheng… - … Pharmaceutica Sinica B, 2021 - Elsevier
Membrane-disruptive peptides/peptidomimetics (MDPs) are antimicrobials or
anticarcinogens that present a general killing mechanism through the physical disruption of …

Polymer-based coatings with integrated antifouling and bactericidal properties for targeted biomedical applications

D Mitra, ET Kang, KG Neoh - ACS Applied Polymer Materials, 2021 - ACS Publications
One of the most detrimental consequences of surface colonization by bacteria is healthcare-
associated infections (HAIs), which contribute to increased patient mortality and morbidity …

Biomimetic antimicrobial polymers: Recent advances in molecular design

C Ergene, K Yasuhara, EF Palermo - Polymer Chemistry, 2018 - pubs.rsc.org
The increasing prevalence of antibiotic-resistant bacterial infections, coupled with the
decline in the number of new antibiotic drug approvals, has created a therapeutic gap that …

Controlling macromolecular structures towards effective antimicrobial polymers

MS Ganewatta, C Tang - Polymer, 2015 - Elsevier
Drug resistance of pathogenic bacteria is a major global problem leading humanity towards
a pre-antibiotic era. Decline in the discovery of novel antibiotics and the lack of a resilient …

Targeted polymer-based antibiotic delivery system: A promising option for treating bacterial infections via macromolecular approaches

T Wang, F Rong, Y Tang, M Li, T Feng, Q Zhou… - Progress in Polymer …, 2021 - Elsevier
Antibiotic therapy is the routine method for treating bacterial infections and has saved
hundreds of millions of lives over the last century. However, low bioavailability, side effects …

Reimagining Chitosan‐Based Antimicrobial Biomaterials to Mitigate Antibiotic Resistance and Alleviate Antibiotic Overuse: A Review

KS Dhlamini, CT Selepe, B Ramalapa… - Macromolecular …, 2024 - Wiley Online Library
This paper reports recent advancements in chitosan‐based antimicrobial biomaterials that
aim to address the issue of antimicrobial resistance (AMR). Today, AMR is one of the most …

Cytotoxicity and antimicrobial activity of oral rinses in vitro

HD Müller, S Eick, A Moritz, A Lussi… - BioMed research …, 2017 - Wiley Online Library
While oral rinses used for cosmetic purposes only do not necessarily have to be antiseptic,
antimicrobial activity is required for medical indications, including oral and periodontal …

Polymeric drugs: Advances in the development of pharmacologically active polymers

J Li, F Yu, Y Chen, D Oupický - Journal of Controlled Release, 2015 - Elsevier
Synthetic polymers play a critical role in pharmaceutical discovery and development.
Current research and applications of pharmaceutical polymers are mainly focused on their …