Non-alcoholic fatty liver disease (NAFLD) is often the hepatic expression of metabolic
syndrome and its comorbidities that comprise, among others, obesity and insulin-resistance …

Mitochondria are considered the 'powerhouses' of cells, generating the essential energy in
the form of adenosine triphosphate that they need for their energy demands. Nevertheless …

Butyrate and R-β-hydroxybutyrate are two related short chain fatty acids naturally found in
mammals. Butyrate, produced by enteric butyric bacteria, is present at millimolar …

Dietary intervention is widely used as a therapeutic approach ranging from the treatment of
neurological disorders to attempts to extend lifespan. The most important effect of various …

Mitochondrial dysfunction is a hallmark of cardiac pathophysiology. Defects in mitochondrial
performance disrupt contractile function, overwhelm myocytes with reactive oxygen species …

A ketogenic diet (KD) could induce nutritional ketosis. Over time, the body will acclimate to
use ketone bodies as a primary fuel to achieve keto-adaptation. Keto-adaptation may …

The ketogenic diet (KD) is a high-fat, low-carbohydrate treatment for medically intractable
epilepsy. One of the hallmark features of the KD is the production of ketone bodies which …

Gut microbiota (GM) is a key contributor to host metabolism and physiology. Data generated
on comparing diseased and healthy subjects have reported changes in the GM profile …

Ketogenic diets are very low carbohydrate, high fat, moderate protein diets used to treat
medication-resistant epilepsy. Growing evidence suggests that one of the ketogenic diet's …

Recently, we demonstrated the capability of the ketogenic diet (KD) to influence the
microRNA (miR) expression profile. Here, we report that KD is able to normalize miR …